The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability.
about
Sirtuins: Sir2-related NAD-dependent protein deacetylasesTIN2, a new regulator of telomere length in human cellsHuman SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycleCharacterization of the CHD family of proteinsDeacetylation of the retinoblastoma tumour suppressor protein by SIRT1Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase.Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeresSIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondriaRNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiaeThe mammalian SIR2alpha protein has a role in embryogenesis and gametogenesisIsolation of a SIR-like gene, SIR-T8, that is overexpressed in thyroid carcinoma cell lines and tissuesAltered sirtuin expression is associated with node-positive breast cancerSIRT6 in DNA repair, metabolism and ageingSilent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-riboseApoptosis-like death in trypanosomatids: search for putative pathways and genes involvedA network of multi-tasking proteins at the DNA replication fork preserves genome stabilitySirt1 and the MitochondriaSirtuin 1 and sirtuin 3: physiological modulators of metabolismThe controversial world of sirtuinsSirtuins in epigenetic regulationStructural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 EnzymesStructure of Sir2Tm bound to a propionylated peptideStructural basis for allosteric stimulation of Sir2 activity by Sir4 bindingStructures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitmentThe glucanosyltransferase Gas1 functions in transcriptional silencing.Localization of Sir2p: the nucleolus as a compartment for silent information regulatorsHst3 is regulated by Mec1-dependent proteolysis and controls the S phase checkpoint and sister chromatid cohesion by deacetylating histone H3 at lysine 56.The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatinGenomic analysis of PIS1 gene expression.Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8.Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo.A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factorsA novel yeast silencer. the 2mu origin of Saccharomyces cerevisiae has HST3-, MIG1- and SIR-dependent silencing activity.Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3.The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases.Telomeric and rDNA silencing in Saccharomyces cerevisiae are dependent on a nuclear NAD(+) salvage pathway.Thiamine biosynthesis in Saccharomyces cerevisiae is regulated by the NAD+-dependent histone deacetylase Hst1.
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P2860
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability.
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
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name
The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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The SIR2 gene family, conserve ...... ion, and chromosome stability.
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C B Brachmann
E E Cameron
J M Sherman
S E Devine
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10.1101/GAD.9.23.2888
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P577
1995-12-01T00:00:00Z