Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
about
Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinaseKu86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response elementXrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IVCrystal structure of the Xrcc4 DNA repair protein and implications for end joiningDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsProkaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair systemLymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombinationRecruitment of Saccharomyces cerevisiae Dnl4-Lif1 complex to a double-strand break requires interactions with Yku80 and the Xrs2 FHA domainDynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4Genome wide distribution of illegitimate recombination events in Kluyveromyces lactisAnalysis of the DNA joining repertoire of Chlorella virus DNA ligase and a new crystal structure of the ligase-adenylate intermediateNEJ1 controls non-homologous end joining in Saccharomyces cerevisiae.Conserved interactions of the splicing factor Ntr1/Spp382 with proteins involved in DNA double-strand break repair and telomere metabolism.Yeast Nej1 is a key participant in the initial end binding and final ligation steps of nonhomologous end joining.A physical and functional interaction between yeast Pol4 and Dnl4-Lif1 links DNA synthesis and ligation in nonhomologous end joining.Rap1 prevents telomere fusions by nonhomologous end joining.Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection.Regulation of repair choice: Cdk1 suppresses recruitment of end joining factors at DNA breaks.Non-homologous end-joining, a sticky affairNHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway.Ku86 is essential in human somatic cells.SIR functions are required for the toleration of an unrepaired double-strand break in a dispensable yeast chromosome.DNA Ligase IV regulates XRCC4 nuclear localization.Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku.End-joining repair of double-strand breaks in Drosophila melanogaster is largely DNA ligase IV independent.DNA polymerase 4 of Saccharomyces cerevisiae is important for accurate repair of methyl-methanesulfonate-induced DNA damageRqh1 blocks recombination between sister chromatids during double strand break repair, independent of its helicase activity.Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding.Double-strand break repair in human cells.Genome-wide screens for sensitivity to ionizing radiation identify the fission yeast nonhomologous end joining factor Xrc4.Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.The role of nonhomologous end-joining components in telomere metabolism in Kluyveromyces lactisHistone modifications and DNA double-strand break repair.Molecular basis of ataxia telangiectasia and related diseases.Lif1 SUMOylation and its role in non-homologous end-joining.V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.Ku affects the ATM-dependent S phase checkpoint following ionizing radiation.Molecular dissection of mitotic recombination in the yeast Saccharomyces cerevisiaeThe Arabidopsis AtLIG4 gene is required for the repair of DNA damage, but not for the integration of Agrobacterium T-DNA
P2860
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P2860
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@ast
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@en
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@nl
type
label
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@ast
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@en
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@nl
prefLabel
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@ast
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@en
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@nl
P1433
P1476
Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks.
@en
P2093
P356
10.1016/S0960-9822(00)00317-1
P407
P577
2000-02-10T00:00:00Z