Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function.
about
Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosisCrystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointThe human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochoresBub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesisLinking kinetochore-microtubule binding to the spindle checkpointSpindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activityBub1-mediated adaptation of the spindle checkpointStructure of human Mad1 C-terminal domain reveals its involvement in kinetochore targetingBub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signalingMad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis.Distinct chromosome segregation roles for spindle checkpoint proteins.Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)atedDNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore.Recognizing chromosomes in trouble: association of the spindle checkpoint protein Bub3p with altered kinetochores and a unique defective centromere.Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment.Identification of mRNAs differentially-expressed between benign and malignant breast tumour cells.Utilizing evolutionary information and gene expression data for estimating gene networks with bayesian network models.The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint functionEvaluating putative mechanisms of the mitotic spindle checkpointThe spindle checkpoint, aneuploidy, and cancer.Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint.Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase.ATM-mediated Mad1 Serine 214 phosphorylation regulates Mad1 dimerization and the spindle assembly checkpoint.mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.Reovirus-induced alterations in gene expression related to cell cycle regulation.An alpha-tubulin mutant demonstrates distinguishable functions among the spindle assembly checkpoint genes in Saccharomyces cerevisiae.Centrosomes and checkpoints: the MPS1 family of kinases.The spindle checkpoint: structural insights into dynamic signalling.Characterization of cell cycle specific protein interaction networks of the yeast 26S proteasome complex by the QTAX strategy.Mad2 and Mad3 cooperate to arrest budding yeast in mitosis.Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response.Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exitThe fission yeast ran GTPase is required for microtubule integrity.How the SAC gets the axe: Integrating kinetochore microtubule attachments with spindle assembly checkpoint signaling.Bipolar orientation of chromosomes in Saccharomyces cerevisiae is monitored by Mad1 and Mad2, but not by Mad3.The composition, functions, and regulation of the budding yeast kinetochoreThe spindle assembly checkpoint in Caenorhabditis elegans: one who lacks Mad1 becomes mad one
P2860
Q21142712-35057715-1084-4D7D-8138-FF43BB90157CQ24297170-A311787E-BDDD-4E1A-B69A-4E6009A3ACD6Q24306626-C2E30884-AEB2-4734-93D7-70DF5DA19FD2Q24534626-4A609BBA-D7B8-41FC-AA07-69D2CFBE678DQ24600680-B56DFE1B-87CA-4324-AC2D-BA1FF9245FF5Q24646166-25EB68EF-40AA-4C57-BF14-6D571CE0C875Q24679269-A30760A2-8197-4398-AEE4-95959589C1EDQ27343104-6C702555-4DC0-43A8-938D-FDE1E6CD0AE8Q27678430-69C82DB0-03D3-458C-BE84-8E4F643FE373Q27680055-F4165892-EA2F-43BD-A222-E2C13643C634Q27930798-06188956-16C9-4591-AF7D-91C6A8AE2210Q27932473-BB3A0508-FD97-48A2-A0F2-BB4AA7D1D8CAQ27932972-F4103240-1B5E-4B17-9906-A2E699D51CDBQ28217564-E7E25334-1B0C-4E71-A2DC-5A5EA780DB8DQ30443388-8D25738D-54DD-44FA-9E15-3AFBDEC7112AQ30452748-231E5F6C-4AB2-4B82-83CE-CD53ACA15CAAQ30653598-DD1C92DA-8494-4800-A8A9-4F3C1D0DCBC2Q30657692-517245B4-F694-48E8-B4F2-527943D2ECF9Q30843044-CAC51472-9B9D-447A-BE6F-B633957DBCBFQ31027460-7E29F196-2BCF-4DB5-9D0A-E52360A5C03BQ33565078-9AC1171D-2A9E-467C-AF1F-C1F27365BF6CQ33772035-9C0595FF-8716-4363-81B1-984C82562C42Q33976673-34C96DE5-2AD9-4398-870B-E1A82C97A7B6Q34040203-CA9D430F-D48C-4DD7-8FC5-8B0A80F983F0Q34040427-31038A2F-6ED7-4012-A00D-A7E7F93EA40EQ34040591-B973DFA5-43AF-495D-9985-2BB35CC69672Q34100729-26EB472D-CE5D-43AA-A580-D76E79FE7344Q34332403-40C3C9F0-203D-41E4-A202-5C99C04139DFQ34615442-FDE2FB8E-3410-4179-9A95-BB81A38F16C9Q34818183-6600BDB1-445E-4E6A-BFB2-06127E5E59BEQ34931754-ABA0577B-5D08-4C13-8F48-B97BFA7DB04DQ35120072-BAF2F133-D029-4E0D-ABE1-7E8A2EC88464Q35751334-3A7F9654-CEF2-4589-AD78-9ADC83FD9B41Q35893417-56C44F7A-F30F-4FA5-85E2-C3D4036418D8Q35936918-9D098F93-3D52-4EA4-9205-682C43A5DDCDQ36326416-EDAA96E3-8B74-4DB7-8146-9B43A38C2BADQ36800295-952AA253-D96F-4EAE-B4BD-94532BDC308FQ36986542-93EE9B09-EA4C-4C13-8DBB-EE0A24C1C5E7Q37063126-AE2637E5-E6B0-4150-A7C8-828D33C44652Q37306927-2EBFC3EB-D11B-4C88-BF43-CAD23BBC0CD3
P2860
Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Complex formation between Mad1 ...... r spindle checkpoint function.
@ast
Complex formation between Mad1 ...... r spindle checkpoint function.
@en
Complex formation between Mad1 ...... r spindle checkpoint function.
@nl
type
label
Complex formation between Mad1 ...... r spindle checkpoint function.
@ast
Complex formation between Mad1 ...... r spindle checkpoint function.
@en
Complex formation between Mad1 ...... r spindle checkpoint function.
@nl
prefLabel
Complex formation between Mad1 ...... r spindle checkpoint function.
@ast
Complex formation between Mad1 ...... r spindle checkpoint function.
@en
Complex formation between Mad1 ...... r spindle checkpoint function.
@nl
P3181
P1433
P1476
Complex formation between Mad1 ...... r spindle checkpoint function.
@en
P2093
K G Hardwick
P3181
P356
10.1016/S0960-9822(00)00515-7
P407
P577
2000-06-01T00:00:00Z