Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
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Understanding the binding properties of an unusual metal-binding protein--a study of bacterial frataxinStructural characterization of metal binding to a cold-adapted frataxinMitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes.Protein stability and dynamics modulation: the case of human frataxinPharmacological screening using an FXN-EGFP cellular genomic reporter assay for the therapy of Friedreich ataxiaStructural, Mechanistic and Coordination Chemistry of Relevance to the Biosynthesis of Iron-Sulfur and Related Iron CofactorsThe in vivo mitochondrial two-step maturation of human frataxin.Limitations in a frataxin knockdown cell model for Friedreich ataxia in a high-throughput drug screenIron-binding activity in yeast frataxin entails a trade off with stability in the alpha1/beta1 acidic ridge regionFriedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities.Frataxin and mitochondrial FeS cluster biogenesis.Normal and Friedreich ataxia cells express different isoforms of frataxin with complementary roles in iron-sulfur cluster assemblyMolecular details of the yeast frataxin-Isu1 interaction during mitochondrial Fe-S cluster assemblyOverlapping binding sites of the frataxin homologue assembly factor and the heat shock protein 70 transfer factor on the Isu iron-sulfur cluster scaffold proteinRescue of the Friedreich ataxia knockout mutation in transgenic mice containing an FXN-EGFP genomic reporter.Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent mannerIron chaperones for mitochondrial Fe-S cluster biosynthesis and ferritin iron storageKey players and their role during mitochondrial iron-sulfur cluster biosynthesisDeficiency in frataxin homologue YFH1 in the yeast Pichia guilliermondii leads to missregulation of iron acquisition and riboflavin biosynthesis and affects sulfate assimilation.Iron-sulfur cluster synthesis, iron homeostasis and oxidative stress in Friedreich ataxia.Loss of cardiolipin leads to perturbation of mitochondrial and cellular iron homeostasisNeurodegeneration in Friedreich's ataxia: from defective frataxin to oxidative stressSiderophore-controlled iron assimilation in the enterobacterium Erwinia chrysanthemi: evidence for the involvement of bacterioferritin and the Suf iron-sulfur cluster assembly machineryOligomeric yeast frataxin drives assembly of core machinery for mitochondrial iron-sulfur cluster synthesisFixing frataxin: 'ironing out' the metabolic defect in Friedreich's ataxiaFrataxin: a protein in search for a function.Human Frataxin Folds Via an Intermediate State. Role of the C-Terminal Region.A helix-coil transition induced by the metal ion interaction with a grafted iron-binding site of the CyaY protein family.Binding of yeast frataxin to the scaffold for Fe-S cluster biogenesis, IsuStructural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly.Assembly of the iron-binding protein frataxin in Saccharomyces cerevisiae responds to dynamic changes in mitochondrial iron influx and stress level.Expression, purification, and characterization of an iron chaperon protein CyaY from Acidithiobacillus ferrooxidans.Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins.A dynamic model of the proteins that form the initial iron-sulfur cluster biogenesis machinery in yeast mitochondria.Zinc and the iron donor frataxin regulate oligomerization of the scaffold protein to form new Fe-S cluster assembly centers.Mechanisms of iron and copper-frataxin interactions.Interactions of iron-bound frataxin with ISCU and ferredoxin on the cysteine desulfurase complex leading to Fe-S cluster assembly.
P2860
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P2860
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@ast
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@en
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@nl
type
label
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@ast
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@en
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@nl
prefLabel
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@ast
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@en
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@nl
P2860
P356
P1433
P1476
Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly.
@en
P2093
Françoise Foury
Mathieu Trincal
P2860
P356
10.1038/SJ.EMBOR.7400881
P407
P577
2007-02-01T00:00:00Z