Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.
about
The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complexCYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligasesA family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligaseReconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP)Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome systemUBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6Polyamine analogues inhibit the ubiquitination of spermidine/spermine N1-acetyltransferase and prevent its targeting to the proteasome for degradationThe products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein familyEvidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasomeGlycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics)The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome systemThe stress response against denatured proteins in the deletion of cytosolic chaperones SSA1/2 is different from heat-shock response in Saccharomyces cerevisiaeCrystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificityThe multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins.UBA 1: an essential yeast gene encoding ubiquitin-activating enzymeA role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae.The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants.Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizymeNovel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiaeFunctional domains of the Rsp5 ubiquitin-protein ligase.The essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4.UBC1 encodes a novel member of an essential subfamily of yeast ubiquitin-conjugating enzymes involved in protein degradation.The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.Centrin/Cdc31 is a novel regulator of protein degradation.Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysisYeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination.The recognition component of the N-end rule pathwayA novel protein modification pathway related to the ubiquitin system.Tmc1 Is a Dynamically Regulated Effector of the Rpn4 Proteotoxic Stress Response.Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.The Ubc3 (Cdc34) ubiquitin-conjugating enzyme is ubiquitinated and phosphorylated in vivoAcute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosolGlobal transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stressOverexpression of VrUBC1, a Mung Bean E2 Ubiquitin-Conjugating Enzyme, Enhances Osmotic Stress Tolerance in ArabidopsisMolecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E2(17)kB) highly expressed in rat testisDifferential regulation of components of the ubiquitin-proteasome pathway during lens cell differentiationListerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociation
P2860
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P2860
Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.
description
1990 nî lūn-bûn
@nan
1990 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@ast
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@en
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@nl
type
label
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@ast
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@en
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@nl
prefLabel
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@ast
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@en
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@nl
P2860
P3181
P1433
P1476
Ubiquitin-conjugating enzymes ...... t-lived and abnormal proteins.
@en
P2093
P2860
P304
P3181
P407
P577
1990-02-01T00:00:00Z