Synthetic lethality with conditional dbp6 alleles identifies rsa1p, a nucleoplasmic protein involved in the assembly of 60S ribosomal subunits.
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Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interactionNog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation stepsDExD/H-box RNA helicases in ribosome biogenesisCharacterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assemblySynchronizing nuclear import of ribosomal proteins with ribosome assemblyRNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1.Dbp9p, a putative ATP-dependent RNA helicase involved in 60S-ribosomal-subunit biogenesis, functionally interacts with Dbp6pThe AAA ATPase Rix7 powers progression of ribosome biogenesis by stripping Nsa1 from pre-60S particles.ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae.SFP1 is involved in cell size modulation in respiro-fermentative growth conditions.Nascent 60S ribosomal subunits enter the free pool bound by Nmd3p.The putative RNA helicase Dbp6p functionally interacts with Rpl3p, Nop8p and the novel trans-acting Factor Rsa3p during biogenesis of 60S ribosomal subunits in Saccharomyces cerevisiae.Characterization of Saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesisThe two proteins Pat1p (Mrt1p) and Spb8p interact in vivo, are required for mRNA decay, and are functionally linked to Pab1p.Dbp10p, a putative RNA helicase from Saccharomyces cerevisiae, is required for ribosome biogenesis.The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeastNovel G-protein complex whose requirement is linked to the translational status of the cell.Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10p.Translational regulator RpL10p/Grc5p interacts physically and functionally with Sed1p, a dynamic component of the yeast cell surface.Npa1p is an essential trans-acting factor required for an early step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae.The Dedicated Chaperone Acl4 Escorts Ribosomal Protein Rpl4 to Its Nuclear Pre-60S Assembly SiteProtein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiaeFunctional interaction between RNA helicase II/Gu(alpha) and ribosomal protein L4.Linear ubiquitin fusion to Rps31 and its subsequent cleavage are required for the efficient production and functional integrity of 40S ribosomal subunits.Mak5 and Ebp2 act together on early pre-60S particles and their reduced functionality bypasses the requirement for the essential pre-60S factor Nsa1.Functional analysis of Saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis.The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machineryRibosome biogenesis in the yeast Saccharomyces cerevisiaeNutritional status modulates box C/D snoRNP biogenesis by regulated subcellular relocalization of the R2TP complexMutations in the TATA-binding protein, affecting transcriptional activation, show synthetic lethality with the TAF145 gene lacking the TAF N-terminal domain in Saccharomyces cerevisiae.The RNA catabolic enzymes Rex4p, Rnt1p, and Dbr1p show genetic interaction with trans-acting factors involved in processing of ITS1 in Saccharomyces cerevisiae pre-rRNA.
P2860
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P2860
Synthetic lethality with conditional dbp6 alleles identifies rsa1p, a nucleoplasmic protein involved in the assembly of 60S ribosomal subunits.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@ast
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@en
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@nl
type
label
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@ast
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@en
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@nl
prefLabel
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@ast
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@en
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@nl
P2093
P2860
P356
P1476
Synthetic lethality with condi ...... bly of 60S ribosomal subunits.
@en
P2093
P2860
P304
P356
10.1128/MCB.19.12.8633
P407
P577
1999-12-01T00:00:00Z