Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling. - Wikidata - wikimedia - TriplyDB

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

http://www.wikidata.org/entity/Q27967666

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Structural Analysis of the 14-3-3ζ/Chibby Interaction Involved in Wnt/β-Catenin Signaling The nuclear envelope LEM-domain protein emerin Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/β-catenin antagonist Chibby Chemokine GPCR signaling inhibits β-catenin during zebrafish axis formation BAR Domain-Containing FAM92 Proteins Interact with Chibby1 To Facilitate Ciliogenesis Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway A Wnt/beta-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation.A role for primary cilia in glutamatergic synaptic integration of adult-born neurons Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function.β-catenin dosage is a critical determinant of tracheal basal cell fate determination.Diversification of importin-α isoforms in cellular trafficking and disease states Drosophila chibby is required for basal body formation and ciliogenesis but not for Wg signaling.Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia.Physiological inhibitors of Wnt signaling.Factors affecting the nuclear localization of β-catenin in normal and malignant tissue.Chibby1 knockdown promotes mesenchymal-to-epithelial transition-like changes.14-3-3 and β-catenin are secreted on extracellular vesicles to activate the oncogenic Wnt pathway.Moonlighting chaperone-like activity of the universal regulatory 14-3-3 proteins.Nuclear roles for cilia-associated proteins.Conformational characterization of the intrinsically disordered protein Chibby: Interplay between structural elements in target recognition.Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells.Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis.Chibby suppresses growth of human SW480 colon adenocarcinoma cells through inhibition of β-catenin signaling.Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression.Thyroid cancer 1 (C8orf4) shows high expression, no mutation and reduced methylation level in lung cancers, and its expression correlates with β-catenin and DNMT1 expression and poor prognosis Generation and characterization of monoclonal antibodies against human Chibby protein.TC-1 (C8orf4) expression is correlated with differentiation in ovarian carcinomas and might distinguish metastatic ovarian from metastatic colorectal carcinomas.Downregulation of nuclear and cytoplasmic Chibby is associated with advanced cervical cancer.C2CD3 binds the mother centriole CBY1 binds beta-catenin XPO1 binds the beta-catenin:CBY complex YWHAZ and XPO1 mediate the nuclear export of beta-catenin Chibby suppresses aerobic glycolysis and proliferation of nasopharyngeal carcinoma via the Wnt/β-catenin-Lin28/let7-PDK1 cascade.New susceptibility loci for cutaneous melanoma risk and progression revealed using a porcine model.

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Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

http://www.wikidata.org/entity/Q27967666

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

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name

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

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Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

@en

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

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type

label

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

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Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

@en

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

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altLabel

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling

@en

prefLabel

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

@ast

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

@en

Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.

@nl

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MBC.E09-05-0437

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Molecular Biology of the Cell

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Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling

@en

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Adaobi Mofunanya

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Feng-Qian Li

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Jason Hall

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Ken-Ichi Takemaru

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P2860

Mechanisms of Receptor-Mediated Nuclear Import and Nuclear Export

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins

Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway

Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

Amino acids C-terminal to the 14-3-3 binding motif in CDC25B affect the efficiency of 14-3-3 binding

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

Inhibition of human immunodeficiency virus Rev and human T-cell leukemia virus Rex function, but not Mason-Pfizer monkey virus constitutive transport element activity, by a mutant human nucleoporin targeted to Crm1

Dimerization of sterol regulatory element-binding protein 2 via the helix-loop-helix-leucine zipper domain is a prerequisite for its nuclear localization mediated by importin beta

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2

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Victoria Fischer

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2009-11-25T00:00:00Z

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19940019

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2808236

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