about
Crystallographic studies of chemically modified nucleic acids: a backward glanceSyntheses of 4'-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4'-thiocytosine.Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidinesThe structural diversity of artificial genetic polymersMetabolic compensation and circadian resilience in prokaryotic cyanobacteriaIntricate protein-protein interactions in the cyanobacterial circadian clockThe steric hypothesis for DNA replication and fluorine hydrogen bonding revisited in light of structural dataMetal ions and flexibility in a viral RNA pseudoknot at atomic resolution2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNASelenium-assisted nucleic acid crystallography: use of phosphoroselenoates for MAD phasing of a DNA structureDirect observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effectsFace-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linkerAn aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injuryWhy does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferaseGene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotideMolecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairingHydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzymeStructure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotolueneCrystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion anglesStructural model of the circadian clock KaiB–KaiC complex and mechanism for modulation of KaiC phosphorylationA Bridging Water Anchors the Tethered 5-(3-Aminopropyl)-2′-deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C·G Base Pair: Implications for Formation of Interstrand 5′-GNC-3′ Cross-Links by Nitrogen Mustards † , ‡Insertion of dNTPs Opposite the 1, N 2 -Propanodeoxyguanosine Adduct by Sulfolobus solfataricus P2 DNA Polymerase IV † ‡Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complexEffects of N2,N2 -dimethylguanosine on RNA structure and stability: Crystal structure of an RNA duplex with tandem m2 2G:A pairsVersatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine AdductsA conformational transition in the structure of a 2′-thiomethyl-modified DNA visualized at high resolutionStructural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct ,Structural and Functional Elucidation of the Mechanism Promoting Error-prone Synthesis by Human DNA Polymerase Opposite the 7,8-Dihydro-8-oxo-2'-deoxyguanosine AdductStructure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXESPairing Geometry of the Hydrophobic Thymine Analogue 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray CrystallographyInterplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNAStructures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and PhosphataseMetal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 fromSulfolobus solfataricusAn Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNAStructural Basis for Proficient Incorporation of dTTP Opposite O6-Methylguanine by Human DNA Polymerase ιUnexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNABypass of Aflatoxin B 1 Adducts by the Sulfolobus solfataricus DNA Polymerase IV
P50
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P50
description
biochemist
@en
hulumtues
@sq
onderzoeker
@nl
հետազոտող
@hy
name
Martin Egli
@ast
Martin Egli
@en
Martin Egli
@es
Martin Egli
@sl
type
label
Martin Egli
@ast
Martin Egli
@en
Martin Egli
@es
Martin Egli
@sl
prefLabel
Martin Egli
@ast
Martin Egli
@en
Martin Egli
@es
Martin Egli
@sl