about
Targeting DNA Replication Stress for Cancer TherapyFunctions of Ubiquitin and SUMO in DNA Replication and Replication StressHow MCM loading and spreading specify eukaryotic DNA replication initiation sitesRescue from replication stress during mitosis.Mutations in CDC45, Encoding an Essential Component of the Pre-initiation Complex, Cause Meier-Gorlin Syndrome and Craniosynostosis.Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication ForksInflammation, DNA Damage, Helicobacter pylori and Gastric Tumorigenesis.Regulation of Replication Fork Advance and Stability by Nucleosome Assembly.Abro1 maintains genome stability and limits replication stress by protecting replication fork stability.Stalled replication forks generate a distinct mutational signature in yeast.Replication fork regression and its regulation.POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologiesSmall cell lung cancer: Time to revisit DNA-damaging chemotherapy.Combining electron microscopy with single molecule DNA fiber approaches to study DNA replication dynamics.Effects of Replication and Transcription on DNA Structure-Related Genetic InstabilityMechanisms of oncogene-induced genomic instability.Moonlighting at replication forks - a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51.Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation.SNM1B/Apollo in the DNA damage response and telomere maintenancePerturbations in the Replication Program Contribute to Genomic Instability in Cancer.Targeting DNA repair and replication stress in the treatment of ovarian cancer.Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity.Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations.Transcriptome guided identification of novel functions of RECQ1 helicase.Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin.Inter-Fork Strand Annealing causes genomic deletions during the termination of DNA replication.Replication fork reversal triggers fork degradation in BRCA2-defective cells.MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells.A priA Mutant Expressed in Two Pieces Has Almost Full Activity in Escherichia coli K-12.A Redox Role for the [4Fe4S] Cluster of Yeast DNA Polymerase δ.The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks.Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells.Replication Fork Reversal: Players and Guardians.Mechanisms of bacterial DNA replication restart.Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex.Building up and breaking down: mechanisms controlling recombination during replication.FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres.Breaking the end: Target the replication stress response at the ALT telomeres for cancer therapy.Collaboration in the actions of Brh2 with resolving functions during DNA repair and replication stress in Ustilago maydis.
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Replication stress: getting back on track
@ast
Replication stress: getting back on track
@en
Replication stress: getting back on track
@nl
type
label
Replication stress: getting back on track
@ast
Replication stress: getting back on track
@en
Replication stress: getting back on track
@nl
prefLabel
Replication stress: getting back on track
@ast
Replication stress: getting back on track
@en
Replication stress: getting back on track
@nl
P2860
P3181
P356
P1476
Replication stress: getting back on track
@en
P2093
Alessandro Vindigni
Matteo Berti
P2860
P2888
P3181
P356
10.1038/NSMB.3163
P407
P577
2016-02-01T00:00:00Z
P6179
1020852341