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The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site

The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site

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Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end The reciprocal regulation between splicing and 3'-end processing RNA recognition by Roquin in posttranscriptional gene regulation FUS-mediated regulation of alternative RNA processing in neurons: insights from global transcriptome analysis The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins The neurogenetics of alternative splicing Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms.The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases.Alternative polyadenylation of mRNA precursors.PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control.Reduced function of the RNA-binding protein FPA rescues a T-DNA insertion mutant in the Arabidopsis ZHOUPI gene by promoting transcriptional read-through.A Detailed Analysis of the BR1 Locus Suggests a New Mechanism for Bolting after Winter in Sugar Beet (Beta vulgaris L.).CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing.Cleavage and polyadenylation specificity factor 30: An RNA-binding zinc-finger protein with an unexpected 2Fe-2S cluster.Poly(A) code analyses reveal key determinants for tissue-specific mRNA alternative polyadenylation The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection.An investigation into the role of ATP in the mammalian pre-mRNA 3' cleavage reaction Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster.Evidence that a threshold of serine/arginine-rich (SR) proteins recruits CFIm to promote rous sarcoma virus mRNA 3' end formation Roles of Sumoylation in mRNA Processing and Metabolism.Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons.The roles of RNA processing in translating genotype to phenotype Splicing regulation and dysregulation of cholinergic genes expressed at the neuromuscular junction.RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms.A Genome-wide Study of "Non-3UTR" Polyadenylation Sites in Arabidopsis thaliana.Exploring the Impact of Cleavage and Polyadenylation Factors on Pre-mRNA Splicing Across Eukaryotes.At the Interface of Three Nucleic Acids: The Role of RNA-Binding Proteins and Poly(ADP-ribose) in DNA Repair.A snoRNA modulates mRNA 3' end processing and regulates the expression of a subset of mRNAs.Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases.Two distinct transcription termination modes dictated by promoters.m(6)A-LAIC-seq reveals the census and complexity of the m(6)A epitranscriptome.Comparative analysis of alternative polyadenylation in S. cerevisiae and S. pombe.Molecular basis for the recognition of the human AAUAAA polyadenylation signal.Activity-Dependent Regulation of Alternative Cleavage and Polyadenylation During Hippocampal Long-Term Potentiation.Distinct roles of Pcf11 zinc-binding domains in pre-mRNA 3'-end processing.U1 snRNP telescripting regulates a size-function-stratified human genome.snoRNAs associate with mRNA 3' processing complex: New wine in old bottles.Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation.

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The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site

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2015 nî lūn-bûn

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2015年の論文

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The end of the message: multip ...... the mRNA polyadenylation site

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James L. Manley

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Yongsheng Shi

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P2860

The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability

A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im

An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries

Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors

Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing

Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits

The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation

Participation of the nuclear cap binding complex in pre-mRNA 3' processing

Crystal structure of a human cleavage factor CFI(m)25/CFI(m)68/RNA complex provides an insight into poly(A) site recognition and RNA looping

Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination

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10.1101/GAD.261974.115

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29

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4421977

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