Discovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agents
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Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plantsNrf2 Is an Attractive Therapeutic Target for Retinal DiseasesReduction-oxidation pathways involved in cancer development: a systematic review of literature reviews.Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy.Drug-Repositioning Screening for Keap1-Nrf2 Binding Inhibitors using Fluorescence Correlation SpectroscopyProtein-protein interfaces are vdW dominant with selective H-bonds and (or) electrostatics towards broad functional specificity.Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease.An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitisLimited genetic diversity in the PvK12 Kelch protein in Plasmodium vivax isolates from Southeast AsiaOxidative stress and chronic inflammation in osteoarthritis: can NRF2 counteract these partners in crime?The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update.The role of modulation of antioxidant enzyme systems in the treatment of neurodegenerative diseases.Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia.Recent progress in the development of small molecule Nrf2 modulators: a patent review (2012-2016).l-Serine potentiates fluoroquinolone activity against Escherichia coli by enhancing endogenous reactive oxygen species production.Expression of redox sensing factor Nrf2 in lung macrophages and type II pneumocytes as a prognostic factor in pneumothorax recurrence.A unique tolerizing dendritic cell phenotype induced by the synthetic triterpenoid CDDO-DFPA (RTA-408) is protective against EAE.Triterpenoids from Aglaia abbreviata exert cytotoxicity and multidrug resistant reversal effect in MCF-7/ADM cells via reactive oxygen species induction and P-glycoprotein inhibitionNeuroprotection through flavonoid: Enhancement of the glyoxalase pathway.Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate.Dicarbonyl stress and glyoxalase enzyme system regulation in human skeletal muscle.Identification of a novel small-molecule Keap1-Nrf2 PPI inhibitor with cytoprotective effects on LPS-induced cardiomyopathy.Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a reviewImportance of the Keap1-Nrf2 pathway in NSCLC: Is it a possible biomarker?Molecular Mechanisms of Lithium Action: Switching the Light on Multiple Targets for Dementia Using Animal ModelsThe mycosporine-like amino acids porphyra-334 and shinorine are antioxidants and direct antagonists of Keap1-Nrf2 bindingDicarbonyl Stress and Glyoxalase-1 in Skeletal Muscle: Implications for Insulin Resistance and Type 2 Diabetes
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P2860
Discovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agents
description
2015 nî lūn-bûn
@nan
2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Discovery of direct inhibitors ...... rapeutic and preventive agents
@ast
Discovery of direct inhibitors ...... rapeutic and preventive agents
@en
Discovery of direct inhibitors ...... rapeutic and preventive agents
@nl
type
label
Discovery of direct inhibitors ...... rapeutic and preventive agents
@ast
Discovery of direct inhibitors ...... rapeutic and preventive agents
@en
Discovery of direct inhibitors ...... rapeutic and preventive agents
@nl
prefLabel
Discovery of direct inhibitors ...... rapeutic and preventive agents
@ast
Discovery of direct inhibitors ...... rapeutic and preventive agents
@en
Discovery of direct inhibitors ...... rapeutic and preventive agents
@nl
P2093
P2860
P3181
P1476
Discovery of direct inhibitors ...... rapeutic and preventive agents
@en
P2093
Dhulfiqar Ali Abed
Haifa Albanyan
Huijuan Jin
Longqin Hu
Melanie Goldstein
P2860
P304
P3181
P356
10.1016/J.APSB.2015.05.008
P407
P577
2015-07-01T00:00:00Z