about
The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillanceAdvances in Autophagy Regulatory MechanismsA dynamic interface between ubiquitylation and cAMP signalingImmediate-early response 5 (IER5) interacts with protein phosphatase 2A and regulates the phosphorylation of ribosomal protein S6 kinase and heat shock factor 1Medium throughput biochemical compound screening identifies novel agents for pharmacotherapy of neurofibromatosis type 1.De novo missense variants in PPP2R5D are associated with intellectual disability, macrocephaly, hypotonia, and autismPatient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathwayAll roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation.T cells and autoimmune kidney disease.Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis.Regulation of β-Catenin Phosphorylation by PR55β in Adenoid Cystic Carcinoma.Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum.miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer.Antitumor effects of metformin via indirect inhibition of protein phosphatase 2A in patients with endometrial cancer.Small molecule activators of protein phosphatase 2A for the treatment of castration-resistant prostate cancer.Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium.Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade.Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression.
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
PP2A: The Wolf in Sheep's Clothing?
@ast
PP2A: The Wolf in Sheep's Clothing?
@en
PP2A: The Wolf in Sheep's Clothing?
@nl
type
label
PP2A: The Wolf in Sheep's Clothing?
@ast
PP2A: The Wolf in Sheep's Clothing?
@en
PP2A: The Wolf in Sheep's Clothing?
@nl
prefLabel
PP2A: The Wolf in Sheep's Clothing?
@ast
PP2A: The Wolf in Sheep's Clothing?
@en
PP2A: The Wolf in Sheep's Clothing?
@nl
P2860
P3181
P356
P1433
P1476
PP2A: The Wolf in Sheep's Clothing?
@en
P2093
Maeve Kiely
Patrick Kiely
P2860
P304
P3181
P356
10.3390/CANCERS7020648
P407
P577
2015-04-10T00:00:00Z