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Mechanisms and role of microRNA deregulation in cancer onset and progression

Mechanisms and role of microRNA deregulation in cancer onset and progression

http://www.wikidata.org/entity/Q28109709

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MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer Significance and therapeutic value of miRNAs in embryonal neural tumors FAM46 proteins are novel eukaryotic non-canonical poly(A) polymerases Nanopharmacology in translational hematology and oncology Vasohibin-1 is identified as a master-regulator of endothelial cell apoptosis using gene network analysis Prognostic value of the MicroRNA regulators Dicer and Drosha in non-small-cell lung cancer: co-expression of Drosha and miR-126 predicts poor survival.Performance comparison of digital microRNA profiling technologies applied on human breast cancer cell lines.Clinical significance of miR-140-5p and miR-193b expression in patients with breast cancer and relationship to IGFBP5.Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice.Distinct Small RNA Signatures in Extracellular Vesicles Derived from Breast Cancer Cell Lines miR-199a-5p confers tumor-suppressive role in triple-negative breast cancer.Paeoniflorin inhibits doxorubicin-induced cardiomyocyte apoptosis by downregulating microRNA-1 expression.Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review).Positive expression of miR-361-5p indicates better prognosis for breast cancer patients.Sex and age differences in the expression of liver microRNAs during the life span of F344 rats.The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities.Circulating MicroRNAs as Biomarkers in Health and Disease.The role of microRNAs in medulloblastoma.Lower expression of miR-218 in human breast cancer is associated with lymph node metastases, higher grades, and poorer prognosis.MicroRNAs: Biomarkers, Diagnostics, and Therapeutics.MicroRNA-195-5p, a new regulator of Fra-1, suppresses the migration and invasion of prostate cancer cells.Reverse engineering gene regulatory networks from measurement with missing values.Macrophage-Mediated Inflammation in Normal and Diabetic Wound Healing.Cyclin-dependent kinase 4 is a novel target in micoRNA-195-mediated cell cycle arrest in bladder cancer cells.Pilot Study of Serum MicroRNA-21 as a Diagnostic and Prognostic Biomarker in Egyptian Breast Cancer Patients.Association between polymorphisms of microRNA-binding sites in integrin genes and gastric cancer in Chinese Han population.Targeting MicroRNA in Cancer Using Plant-Based Proanthocyanidins.MicroRNA‑643 regulates the expression of ZEB1 and inhibits tumorigenesis in osteosarcoma.Prenatal and neonatal exposure to perfluorooctane sulfonic acid results in aberrant changes in miRNA expression profile and levels in developing rat livers.Triptolide Inhibits Lung Cancer Cell Migration, Invasion, and Metastasis.miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer.Epigenetic reprogramming in liver fibrosis and cancer.MiR-199a targeting ROCK1 to affect kidney cell proliferation, invasion and apoptosis.RNA Therapeutics in Oncology: Advances, Challenges, and Future Directions.Role of phytochemicals in the modulation of miRNA expression in cancer.The political implications of epigenetics.Research on miRNA-195 and target gene CDK6 in oral verrucous carcinoma.Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of invasive breast cancer.

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Mechanisms and role of microRNA deregulation in cancer onset and progression

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Mechanisms and role of microRNA deregulation in cancer onset and progression

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Mechanisms and role of microRNA deregulation in cancer onset and progression

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Mechanisms and role of microRNA deregulation in cancer onset and progression

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Mechanisms and role of microRNA deregulation in cancer onset and progression

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Genetics and Molecular Biology

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Mechanisms and role of microRNA deregulation in cancer onset and progression

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Andre L Carvalho

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Ismael Dale C Guerreiro

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Marcelo Campos

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Naiara C Nogueira de Souza

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Silvana Gisele P de Campos

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

A microRNA expression signature of human solid tumors defines cancer gene targets

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer

MiR-15a and miR-16-1 cluster functions in human leukemia

A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

RAS is regulated by the let-7 microRNA family

A microRNA polycistron as a potential human oncogene

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10.1590/S1415-47572011000300001

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Edenir Inêz Palmero

Márcia M C Marques

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