Phenylalanine hydroxylase-stimulating protein/pterin-4 alpha-carbinolamine dehydratase from rat and human liver. Purification, characterization, and complete amino acid sequence
about
Tetrahydrobiopterin biosynthesis, regeneration and functionsHyperphenylalaninemia with high levels of 7-biopterin is associated with mutations in the PCBD gene encoding the bifunctional protein pterin-4a-carbinolamine dehydratase and transcriptional coactivator (DCoH).The bifunctional DCOH protein binds to HNF1 independently of its 4-alpha-carbinolamine dehydratase activityStudies on the enzymatic and transcriptional activity of the dimerization cofactor for hepatocyte nuclear factor 1Hyperphenylalaninemia due to defects in tetrahydrobiopterin metabolism: molecular characterization of mutations in 6-pyruvoyl-tetrahydropterin synthaseAlkylglycerol monooxygenaseThree-dimensional structure of the bifunctional protein PCD/DCoH, a cytoplasmic enzyme interacting with transcription factor HNF1Characterization of the wild-type form of 4a-carbinolamine dehydratase and two naturally occurring mutants associated with hyperphenylalaninemiaA unique dual activity amino acid hydroxylase in Toxoplasma gondii.Tetrahydrobiopterin in cardiovascular health and disease.Using comparative genomics to uncover new kinds of protein-based metabolic organelles in bacteria.Pseudomonas aeruginosa possesses homologues of mammalian phenylalanine hydroxylase and 4 alpha-carbinolamine dehydratase/DCoH as part of a three-component gene cluster.Interactions with the bifunctional interface of the transcriptional coactivator DCoH1 are kinetically regulated.Overexpression of pterin-4a-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 in human colon cancer.Identification of hepatic nuclear factor 1 binding sites in the 5' flanking region of the human phenylalanine hydroxylase gene: implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system.Role of the phenylalanine-hydroxylating system in aromatic substance degradation and lipid metabolism in the oleaginous fungus Mortierella alpinaSynthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.Effects of dietary glycerol on the expression of pterin carbinolamine dehydratase in the ratEnhanced synthesis of 5-hydroxy-l-tryptophan through tetrahydropterin regeneration.Structure and function of the aromatic amino acid hydroxylases.Differential expression of chicken dimerization cofactor of hepatocyte nuclear factor-1 (DcoH) and its novel counterpart, DcoHalpha.4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O
P2860
Q24531994-EC014CBE-2847-4941-97F4-BC38E7365D12Q24538999-75EECE64-9CBA-4D30-A05E-EDA5A3819306Q24544517-8375DDF3-C46E-4D6B-8D60-2B91B365C0E5Q24633231-683DF90C-467F-4D55-814F-69DF6C4D6303Q24672904-278FF7CE-8EFB-4583-A8D5-A23CEE003479Q26825422-F7A82A02-3FD1-42D0-A1C7-A054845987F0Q28115243-A29EF054-B25F-43CB-B60F-2E064DF88269Q28277309-E5195492-F0D0-44BC-AB20-C3700CD5C560Q33416807-C4858530-D184-4AE2-96EA-370E242D44AAQ33687812-AAA16DBB-6837-4A3E-8A88-2316A1013F93Q34314123-A6C5ADFB-F885-4E02-9628-D8C50E51DE6AQ35045020-23F70B8B-A5F3-409B-B82A-6481AD6AC66AQ35080345-2DAA0AF7-75CC-4D2F-9822-927A0B38EEEFQ35788230-9E5661E0-01B8-4F06-835B-A7167F908C39Q35868114-783023D7-DE9B-4719-9276-0906131BB5DEQ36936418-ED886181-0980-4A68-AF47-0217806D3C5DQ37873087-32BB72BE-34ED-474A-99CC-DC22D2E7AAF4Q38355818-581ADF87-2D7A-44E9-837D-097BD08EEB2AQ39829968-77F74748-FB2A-4624-B350-0392CD516AAAQ40375232-4508668F-DEAE-44EB-B6CA-06195B301290Q40822373-5C2C5C8B-002E-4E75-862E-345A6372E46AQ50295028-75C1A88F-632E-45BF-954D-089A01A773C8
P2860
Phenylalanine hydroxylase-stimulating protein/pterin-4 alpha-carbinolamine dehydratase from rat and human liver. Purification, characterization, and complete amino acid sequence
description
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1993
@ast
im März 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/03/05)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/03/05)
@nl
наукова стаття, опублікована в березні 1993
@uk
name
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@ast
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@en
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@nl
type
label
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@ast
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@en
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@nl
prefLabel
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@ast
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@en
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@nl
P2093
P1476
Phenylalanine hydroxylase-stim ...... d complete amino acid sequence
@en
P2093
Curtius HC
Heizmann CW
Hunziker P
Neuheiser F
P304
P407
P50
P577
1993-03-01T00:00:00Z