FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association
about
Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNAA highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2PIGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1)Regulation of XIAP translation and induction by MDM2 following irradiationAltered synaptic plasticity in a mouse model of fragile X mental retardationOligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2PThe c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteinsIsolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complexRibosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionFragile X syndrome: loss of local mRNA regulation alters synaptic development and functionFMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autismFragile x syndromeInhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice.Muscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblastInteraction of Staufen1 with the 5' end of mRNA facilitates translation of these RNAsRNA Secondary Structure Modulates FMRP's Bi-Functional Role in the MicroRNA PathwayRNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndromeThe pathophysiology of fragile X (and what it teaches us about synapses)Channelopathies and dendritic dysfunction in fragile X syndrome.The unstable repeats--three evolving faces of neurological diseaseCharacterization of fragile X mental retardation protein recruitment and dynamics in Drosophila stress granulesStructural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeFragile X mental retardation protein: A paradigm for translational control by RNA-binding proteinsSubcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolinKissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodiesDicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAsIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinMOV10 and FMRP regulate AGO2 association with microRNA recognition elementsFMRP targets distinct mRNA sequence elements to regulate protein expressionA novel function for fragile X mental retardation protein in translational activationTranslational regulation of the human achaete-scute homologue-1 by fragile X mental retardation proteinFragile X mental retardation protein FMRP binds mRNAs in the nucleusDifferent targets for the fragile X-related proteins revealed by their distinct nuclear localizationsThe fragile X gene and its functionIdentification of mRNA/protein (mRNP) complexes containing Puralpha, mStaufen, fragile X protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motorFrom mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndromeLocalization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neuronsPurified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein
P2860
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P2860
FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association
description
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1997
@ast
scientific journal article
@en
vedecký článok (publikovaný 1997/12/01)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/12/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в грудні 1997
@uk
مقالة علمية (نشرت في ديسمبر 1997)
@ar
name
FMRP associates with polyribos ...... ome abolishes this association
@ast
FMRP associates with polyribos ...... ome abolishes this association
@en
FMRP associates with polyribos ...... ome abolishes this association
@nl
type
label
FMRP associates with polyribos ...... ome abolishes this association
@ast
FMRP associates with polyribos ...... ome abolishes this association
@en
FMRP associates with polyribos ...... ome abolishes this association
@nl
prefLabel
FMRP associates with polyribos ...... ome abolishes this association
@ast
FMRP associates with polyribos ...... ome abolishes this association
@en
FMRP associates with polyribos ...... ome abolishes this association
@nl
P2093
P3181
P1433
P1476
FMRP associates with polyribos ...... ome abolishes this association
@en
P2093
D. E. Eberhart
H. E. Malter
S. T. Warren
P304
P3181
P356
10.1016/S1097-2765(00)80012-X
P577
1997-12-01T00:00:00Z