Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells
about
Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathwaysThe beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assemblyThe Saccharomyces cerevisiae TIF6 gene encoding translation initiation factor 6 is required for 60S ribosomal subunit biogenesis.The Saccharomyces cerevisiae homologue of mammalian translation initiation factor 6 does not function as a translation initiation factor.The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrinsNischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migrationRACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiencyeIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcriptionPost-transcriptional regulation of cadherin-11 expression by GSK-3 and beta-catenin in prostate and breast cancer cells.Extracellular matrix signaling: integration of form and function in normal and malignant cellsAn integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.The translation factor eIF6 is a Notch-dependent regulator of cell migration and invasionSBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6Expression and activity of eIF6 trigger malignant pleural mesothelioma growth in vivo.Involvement of eIF6 in external mechanical stretch-mediated murine dermal fibroblast function via TGF-β1 pathway.Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation.The biological roles of ITGB4BP and its potential effect on fibrosis.Eukaryotic translation initiation factors and cancer.The role of eukaryotic translation initiation factor 6 in tumorsAltered eIF6 and Dicer expression is associated with clinicopathological features in ovarian serous carcinoma patients.Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation.p27(BBP)/eIF6 acts as an anti-apoptotic factor upstream of Bcl-2 during Xenopus laevis development.Cloning and expression of bovine imc-415 cDNA from mammary gland.Cytoskeletal proteins associate with components of the ribosomal maturation and translation apparatus in Xenopus stage I oocytes.Eukaryotic initiation factor 6 selectively regulates Wnt signaling and beta-catenin protein synthesis.Tagging of functional ribosomes in living cells by HaloTag® technology.GABP complex regulates transcription of eIF6 (p27BBP), an essential trans-acting factor in ribosome biogenesis
P2860
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P2860
Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells
description
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1997
@ast
im November 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/11/28)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/11/28)
@nl
наукова стаття, опублікована в листопаді 1997
@uk
name
Isolation of a novel beta4 int ...... expressed in epithelial cells
@ast
Isolation of a novel beta4 int ...... expressed in epithelial cells
@en
Isolation of a novel beta4 int ...... expressed in epithelial cells
@nl
type
label
Isolation of a novel beta4 int ...... expressed in epithelial cells
@ast
Isolation of a novel beta4 int ...... expressed in epithelial cells
@en
Isolation of a novel beta4 int ...... expressed in epithelial cells
@nl
prefLabel
Isolation of a novel beta4 int ...... expressed in epithelial cells
@ast
Isolation of a novel beta4 int ...... expressed in epithelial cells
@en
Isolation of a novel beta4 int ...... expressed in epithelial cells
@nl
P2093
P2860
P3181
P356
P1476
Isolation of a novel beta4 int ...... expressed in epithelial cells
@en
P2093
P2860
P304
30314-30321
P3181
P356
10.1074/JBC.272.48.30314
P407
P577
1997-11-01T00:00:00Z