Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
about
The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locusRearranged immunoglobulin heavy chain variable region (VH) pseudogene that deletes the second complementarity-determining regionConservation of sequence in recombination signal sequence spacersConservation of an immunoglobulin variable-region gene family indicates a specific, noncoding functionCloning of a human autoimmune response: preparation and sequencing of a human anti-thyroglobulin autoantibody using a combinatorial approach.Sequence analysis of monoclonal antibodies derived from a patient with idiopathic thrombocytopenic purpura.Characterization of a complete immunoglobulin heavy-chain variable region germ-line gene of rainbow trout.Molecular basis of an autoantibody-associated restriction fragment length polymorphism that confers susceptibility to autoimmune diseasesMultiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter.Human heavy-chain variable region gene family nonrandomly rearranged in familial chronic lymphocytic leukemia.Sequences closely related to an immunoglobulin gene promoter/enhancer element occur also upstream of other eukaryotic and of prokaryotic genes.Complete protein sequences of the variable regions of the cloned heavy and light chains of a human anti-cytomegalovirus antibody reveal a striking similarity to human monoclonal rheumatoid factors of the Wa idiotypic family.A fetally expressed immunoglobulin VH1 gene belongs to a complex set of alleles.Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypesEvidence for gene conversion among immunoglobulin heavy chain variable region genesGenetic basis for expression of the idiotypic network. One unique Ig VH germline gene accounts for the major family of Ab1 and Ab3 (Ab1') antibodies of the GAT system.Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene.Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, BOR and KAS of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segmentsVH gene organization in a relict species, the coelacanth Latimeria chalumnae: evolutionary implications.Immunoglobulin VH gene structure and diversity in Heterodontus, a phylogenetically primitive shark.Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family.Light chain germ-line genes and the immune response to 2-phenyloxazolone.Composite human VK genes and a model of their evolution.Germ line maintenance of the pseudogene donor pool for somatic immunoglobulin gene conversion in chickensDiagnosis of lymphoma in paraffin wax sections by nested PCR and immunohistochemistryPolymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes.Molecular characterization of five human anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response.Complete nucleotide sequences of three VH genes in Caiman, a phylogenetically ancient reptile: evolutionary diversification in coding segments and variation in the structure and organization of recombination elementsPossible involvement of human D minigenes in the first complementarity-determining region of kappa light chains.Antigen-binding specificities of antibodies are primarily determined by seven residues of VH.Human heavy chain variable region gene diversity, organization, and expression.Anti-DNA antibodies, autoimmunity and the immunoglobulin repertoire.Polymorphisms of immunologically relevant loci in human disease. Autoimmunity and human heavy chain variable regions.The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA.Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus.Conservation and divergence of immunoglobulin VH pseudogenes.Allelic immunoglobulin VH genes in two mouse strains: possible germline gene recombination.Development of a highly sensitive assay, based on the polymerase chain reaction, for rare B-lymphocyte clones in a polyclonal population.The human immunoglobulin VH7 gene family consists of a small, polymorphic group of six to eight gene segments dispersed throughout the VH locus.
P2860
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P2860
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
description
1983 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1983 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1983
@ast
im Februar 1983 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1983/02/01)
@sk
vědecký článek publikovaný v roce 1983
@cs
wetenschappelijk artikel (gepubliceerd op 1983/02/01)
@nl
наукова стаття, опублікована в лютому 1983
@uk
name
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@ast
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@en
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@nl
type
label
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@ast
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@en
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@nl
prefLabel
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@ast
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@en
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@nl
P2093
P2860
P356
P1476
Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups
@en
P2093
P2860
P304
P356
10.1073/PNAS.80.3.855
P407
P577
1983-02-01T00:00:00Z