Primary structure of a human trifunctional enzyme. Isolation of a cDNA encoding methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase
about
Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary callsCloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutationsA polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth DefecChromosomal localization of the gene for the human trifunctional enzyme, methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetaseFunction of yeast cytoplasmic C1-tetrahydrofolate synthaseALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenaseMitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryosMammalian MTHFD2L encodes a mitochondrial methylenetetrahydrofolate dehydrogenase isozyme expressed in adult tissuesPhylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymesAssociation between MTHFD1 G1958A polymorphism and neural tube defects susceptibility: a meta-analysis.Plasma folate, related genetic variants, and colorectal cancer risk in EPIC.Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects.Mthfd1 is a modifier of chemically induced intestinal carcinogenesis.Genetic polymorphisms involved in folate metabolism and maternal risk for down syndrome: a meta-analysisGenetic and physiologic analysis of a formyl-tetrahydrofolate synthetase mutant of Streptococcus mutansAnalysis of the promoter region of the gene encoding NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolaseLabel-free LC-MS analysis of HER2+ breast cancer cell line response to HER2 inhibitor treatment.Sequence and expression of the gene for N10-formyltetrahydrofolate synthetase from Clostridium cylindrosporum.Molecular genetic analysis of Saccharomyces cerevisiae C1-tetrahydrofolate synthase mutants reveals a noncatalytic function of the ADE3 gene product and an additional folate-dependent enzyme.MTHFD1 controls DNA methylation in Arabidopsis.Association of methylenetetrahydrofolate dehydrogenase 1 polymorphisms with cancer: a meta-analysisMthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism.FDH: an aldehyde dehydrogenase fusion enzyme in folate metabolism.The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major.Analysis of the MTHFD1 promoter and risk of neural tube defects.Effects of lithium chloride on the gene expression profiles in Drosophila heads.Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cellsGenetic polymorphisms and folate status.Genetics of the serine cycle in Methylobacterium extorquens AM1: identification of sgaA and mtdA and sequences of sgaA, hprA, and mtdA.One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate10-formylTHF polyglutamate <=> 5;10-methenylTHF polyglutamate + H2O5;10-methenylTHF polyglutamate + NADPH + H+ <=> 5;10-methyleneTHF polyglutamate + NADP+5;10-methyleneTHF polyglutamate + NADP+ <=> 5;10-methenylTHF polyglutamate + NADPH + H+5;10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate
P2860
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P2860
Primary structure of a human trifunctional enzyme. Isolation of a cDNA encoding methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase
description
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1988
@ast
im November 1988 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1988/11/05)
@sk
vědecký článek publikovaný v roce 1988
@cs
wetenschappelijk artikel (gepubliceerd op 1988/11/05)
@nl
наукова стаття, опублікована в листопаді 1988
@uk
name
Primary structure of a human t ...... myltetrahydrofolate synthetase
@ast
Primary structure of a human t ...... myltetrahydrofolate synthetase
@en
Primary structure of a human t ...... myltetrahydrofolate synthetase
@nl
type
label
Primary structure of a human t ...... myltetrahydrofolate synthetase
@ast
Primary structure of a human t ...... myltetrahydrofolate synthetase
@en
Primary structure of a human t ...... myltetrahydrofolate synthetase
@nl
prefLabel
Primary structure of a human t ...... myltetrahydrofolate synthetase
@ast
Primary structure of a human t ...... myltetrahydrofolate synthetase
@en
Primary structure of a human t ...... myltetrahydrofolate synthetase
@nl
P2093
P3181
P1476
Primary structure of a human t ...... myltetrahydrofolate synthetase
@en
P2093
P304
15946-15950
P3181
P407
P577
1988-11-01T00:00:00Z