Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
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Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion proteinMOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomainMolecular architecture of quartet MOZ/MORF histone acetyltransferase complexesMOZ-TIF2 inhibits transcription by nuclear receptors and p53 by impairment of CBP functionMOZ and MORF, two large MYSTic HATs in normal and cancer stem cellsWhole-exome-sequencing identifies mutations in histone acetyltransferase gene KAT6B in individuals with the Say-Barber-Biesecker variant of Ohdo syndromeProtein lysine acetylation by p300/CBPGain-of-function mutation of chromatin regulators as a tumorigenic mechanism and an opportunity for therapeutic interventionRegulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Diseaset(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemiaNovel KAT6B-KANSL1 fusion gene identified by RNA sequencing in retroperitoneal leiomyoma with t(10;17)(q22;q21)Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesisAn emerging role for bromodomain-containing proteins in chromatin regulation and transcriptional control of adipogenesis.Histones: Controlling Tumor Signaling CircuitryFusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13).Leukaemogenesis: more than mutant genesCrystallization and preliminary X-ray diffraction analysis of the BRPF1 bromodomain in complex with its H2AK5ac and H4K12ac histone-peptide ligands.Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes.Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain.The MOZ histone acetyltransferase in epigenetic signaling and disease.Bromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammationMales absent on the first (MOF): from flies to humans.Chromatin modification, leukaemia and implications for therapy.Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching.The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases.Therapy related acute myeloid leukemia with t(10:16): a rare entityHistone modifications and DNA double-strand break repair.Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatinPreparation of polyclonal antibody specific for BRD7 and detection of its expression pattern in the human fetus.Epigenetic events in malignant melanoma.The therapeutic uses of chromatin-modifying agents.Cancer genetics of epigenetic genes.The MYST family of histone acetyltransferases and their intimate links to cancer.Epigenetic regulation of normal and malignant hematopoiesis.MYST family histone acetyltransferases take center stage in stem cells and development.Crosstalk between epigenetic readers regulates the MOZ/MORF HAT complexes.Emerging role of epigenetic therapies in cutaneous T-cell lymphomas.Bromodomains as therapeutic targets.
P2860
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P2860
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
description
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Februar 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/02/15)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/02/15)
@nl
наукова стаття, опублікована в лютому 2001
@uk
مقالة علمية (نشرت في 15-2-2001)
@ar
name
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@ast
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@en
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@nl
type
label
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@ast
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@en
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@nl
prefLabel
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@ast
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@en
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@nl
P2093
P50
P356
P1476
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)
@en
P2093
B Strömbeck
F Mitelman
M Isaksson
R Billström
U Samuelsson
P304
P356
10.1093/HMG/10.4.395
P577
2001-02-01T00:00:00Z