Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
about
Calpain activity is essential in skin wound healing and contributes to scar formation.Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown.Skin-Derived C-Terminal Filaggrin-2 Fragments Are Pseudomonas aeruginosa-Directed Antimicrobials Targeting Bacterial Replication.Bacterial calpains and the evolution of the calpain (C2) family of peptidasesIn a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification.The stratum corneum comprises three layers with distinct metal-ion barrier properties.From genetics to treatment of eosinophilic esophagitis.Recent Positive Selection in Genes of the Mammalian Epidermal Differentiation Complex Locus.Modulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase-AIF pathway.Filaggrin - revisited.Cytokines and the skin barrier.iTRAQ-based quantitative proteomics of stratum corneum of dandruff scalp reveals new insights into its aetiology and similarities with atopic dermatitis.Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment.Immediate and extended effects of abrasion on stratum corneum natural moisturizing factor.Immediate and extended effects of sodium lauryl sulphate exposure on stratum corneum natural moisturizing factor.Variation in the activities of late stage filaggrin processing enzymes, calpain-1 and bleomycin hydrolase, together with pyrrolidone carboxylic acid levels, corneocyte phenotypes and plasmin activities in non-sun-exposed and sun-exposed facial stratIncreased filaggrin-metabolizing enzyme activity in atopic skin: a pilot study using a canine model of atopic dermatitis.Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair.Murine filaggrin-2 is involved in epithelial barrier function and down-regulated in metabolically induced skin barrier dysfunction.Peeling skin syndrome associated with novel variant in FLG2 gene.Expression of bleomycin hydrolase in keratinization disorders.Filaggrin gene mutations in African Americans with both ichthyosis vulgaris and atopic dermatitis.
P2860
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P2860
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
description
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2011
@ast
im Juli 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/07/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/07/01)
@nl
наукова стаття, опублікована в липні 2011
@uk
name
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@ast
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@en
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@nl
type
label
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@ast
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@en
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@nl
prefLabel
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@ast
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@en
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@nl
P2093
P2860
P50
P921
P356
P1476
Deimination of human filaggrin-2 promotes its proteolysis by calpain 1
@en
P2093
Anne-Marie Schmitt
Britta Hansmann
Hidenari Takahara
Julie Henry
Marie-Claire Méchin
Odile Burlet-Schiltz
Stéfana Balica
Valérie Pendaries
P2860
P304
23222-23233
P356
10.1074/JBC.M110.197400
P407
P577
2011-04-29T00:00:00Z