LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein
about
Latent TGF-β binding protein-2 is essential for the development of ciliary zonule microfibrilsHuman eye development is characterized by coordinated expression of fibrillin isoformsLatent TGF-beta-binding protein 2 binds to DANCE/fibulin-5 and regulates elastic fiber assemblyLatent TGF-β-binding proteinsA Mutation in LTBP2 Causes Congenital Glaucoma in Domestic Cats (Felis catus)Elastin in the LiverADAMTS proteins as modulators of microfibril formation and functionLTBP2 null mutations in an autosomal recessive ocular syndrome with megalocornea, spherophakia, and secondary glaucomaIdentification of Novel Variants in LTBP2 and PXDN Using Whole-Exome Sequencing in Developmental and Congenital GlaucomaGenomic patterns of introgression in rainbow and westslope cutthroat trout illuminated by overlapping paired-end RAD sequencingTgfbeta2 and 3 are coexpressed with their extracellular regulator Ltbp1 in the early limb bud and modulate mesodermal outgrowth and BMP signaling in chicken embryos.Defining elastic fiber interactions by molecular fishing: an affinity purification and mass spectrometry approach.Biogenesis and function of fibrillin assemblies.Whole exome sequencing identifies a novel splice-site mutation in ADAMTS17 in an Indian family with Weill-Marchesani syndrome.Unraveling the mechanism of elastic fiber assembly: The roles of short fibulinsImmobilized metal affinity chromatography co-purifies TGF-β1 with histidine-tagged recombinant extracellular proteinsLinkage of regulators of TGF-β activity in the fetal ovary to polycystic ovary syndromeLTBP-2 Has a Single High-Affinity Binding Site for FGF-2 and Blocks FGF-2-Induced Cell Proliferation.Osteopontin and latent-TGF β binding-protein 2 as potential diagnostic markers for HBV-related hepatocellular carcinoma.Fibrillin-containing microfibrils are key signal relay stations for cell function.Null mutations in LTBP2 cause primary congenital glaucoma.Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activationGenetic and gene expression analyses of the polycystic ovary syndrome candidate gene fibrillin-3 and other fibrillin family members in human ovaries.TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs.LTBPs, more than just an escort service.The microfibril hypothesis of glaucoma: implications for treatment of elevated intraocular pressure.Latent transforming growth factor-β binding proteins (LTBP-1 and LTBP-2) and gingiva keratinization.Primary congenital and developmental glaucomas.The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome.Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1.The distribution of fibrillin-2 and LTBP-2, and their co-localisation with fibrillin-1 in adult bovine tail disc.A microfibril assembly assay identifies different mechanisms of dominance underlying Marfan syndrome, stiff skin syndrome and acromelic dysplasiasGene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling.NMR spectroscopic and bioinformatic analyses of the LTBP1 C-terminus reveal a highly dynamic domain organisation.Colocalization in vivo and association in vitro of perlecan and elastin.Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.Nifedipine induces periostin expression in gingival fibroblasts through TGF-beta.Backbone ¹H, ¹³C and ¹⁵N resonance assignment of the C-terminal EGF-cbEGF pair of LTBP1 and flanking residues.A Central Bioactive Region of LTBP-2 Stimulates the Expression of TGF-β1 in Fibroblasts via Akt and p38 Signalling Pathways.Structural and compositional diversity of fibrillin microfibrils in human tissues.
P2860
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P2860
LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein
description
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Mai 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/05/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/05/01)
@nl
наукова стаття, опублікована в травні 2007
@uk
مقالة علمية (نشرت في مايو 2007)
@ar
name
LTBP-2 specifically interacts ...... to this microfibrillar protein
@ast
LTBP-2 specifically interacts ...... to this microfibrillar protein
@en
LTBP-2 specifically interacts ...... to this microfibrillar protein
@nl
type
label
LTBP-2 specifically interacts ...... to this microfibrillar protein
@ast
LTBP-2 specifically interacts ...... to this microfibrillar protein
@en
LTBP-2 specifically interacts ...... to this microfibrillar protein
@nl
prefLabel
LTBP-2 specifically interacts ...... to this microfibrillar protein
@ast
LTBP-2 specifically interacts ...... to this microfibrillar protein
@en
LTBP-2 specifically interacts ...... to this microfibrillar protein
@nl
P2093
P3181
P1433
P1476
LTBP-2 specifically interacts ...... to this microfibrillar protein
@en
P2093
Eric Hanssen
Mark A. Gibson
Rena Hirani
P304
P3181
P356
10.1016/J.MATBIO.2006.12.006
P577
2007-05-01T00:00:00Z