Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization
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DCDC2 Mutations Cause Neonatal Sclerosing CholangitisMutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent NephronophthisisAn organelle-specific protein landscape identifies novel diseases and molecular mechanismsStructural and Functional Recovery of Sensory Cilia in C. elegans IFT Mutants upon Aging.Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish.Copy-Number Variation Contributes to the Mutational Load of Bardet-Biedl SyndromeDrosophila sensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults.Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility.Chlamydomonas IFT25 is dispensable for flagellar assembly but required to export the BBSome from flagella.The Intraflagellar Transport Machinery.The T cell IFT20 interactome reveals new players in immune synapse assembly.Ciliopathies.Primary Cilia and Mammalian Hedgehog Signaling.Photoreceptor Cilia and Retinal Ciliopathies.Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex.Ciliopathy-associated IQCB1/NPHP5 protein is required for mouse photoreceptor outer segment formation.IFT54 regulates IFT20 stability but is not essential for tubulin transport during ciliogenesis.The exocyst is required for photoreceptor ciliogenesis and retinal development.Expanding the genetic architecture and phenotypic spectrum in the skeletal ciliopathies.IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.Primary cilia proteins: ciliary and extraciliary sites and functions.Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies.Integrin α8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells.Keeping an Eye on Bardet-Biedl Syndrome: A Comprehensive Review of the Role of Bardet-Biedl Syndrome Genes in the Eye.Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.CRISPR/Cas9-mediated genomic editing of Cluap1/IFT38 reveals a new role in actin arrangement.Ift172 conditional knockout mice exhibit rapid retinal degeneration and protein trafficking defects.Genetic Renal Diseases: The Emerging Role of Zebrafish ModelsThe Reissner Fiber in the Cerebrospinal Fluid Controls Morphogenesis of the Body Axis
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Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization
description
2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans Nature Communications
@fr
artículu científicu espublizáu en 2015
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im Oktober 2015 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2015/10/21)
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vědecký článek publikovaný v roce 2015
@cs
wetenschappelijk artikel (gepubliceerd op 2015/10/21)
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наукова стаття, опублікована в жовтні 2015
@uk
name
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@ast
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@en
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@nl
type
label
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@ast
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@en
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@nl
prefLabel
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@ast
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@en
Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
@nl
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Mutations in TRAF3IP1/IFT54 re ...... s in microtubule stabilization
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Anita Becker-Heck
Bolan Linghu
Edward J Oakeley
Elisabeth Cassuto
Emilie Filhol
Fabrizio Serluca
Friedhelm Hildebrandt
Iain A Drummond
Jan Halbritter
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10.1038/NCOMMS9666
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2015-10-21T00:00:00Z
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1018065360