A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells
about
Restoration of high-level transport activity by human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier functionBiology of the major facilitative folate transporters SLC19A1 and SLC46A1Functional interactions between arginine-133 and aspartate-88 in the human reduced folate carrier: evidence for a charge-pair associationH+-coupled nutrient, micronutrient and drug transporters in the mammalian small intestineIntestinal absorption of water-soluble vitamins in health and diseaseA wide spectrum of clinical and brain MRI findings in patients with SLC19A3 mutations.The proton-coupled folate transporter: physiological and pharmacological roles.The obligatory intestinal folate transporter PCFT (SLC46A1) is regulated by nuclear respiratory factor 1.Mechanisms of membrane transport of folates into cells and across epithelia.SLC19A1 pharmacogenomics summary.Folate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors.The intestinal absorption of folates.Structure and function of the reduced folate carrier a paradigm of a major facilitator superfamily mammalian nutrient transporter.Subcellular localization and distribution of the reduced folate carrier in normal rat tissuesDiagnosis of Coronary Heart Diseases Using Gene Expression Profiling; Stable Coronary Artery Disease, Cardiac Ischemia with and without Myocardial Necrosis.Contribution of tumoral and host solute carriers to clinical drug response.The RFC1 80G>A, among Common One-Carbon Polymorphisms, Relates to Survival Rate According to DNA Global Methylation in Primary Liver Cancers.Folates in Plants: Research Advances and Progress in Crop BiofortificationFolate binding protein: molecular characterization and transcript distribution in pig liver, kidney and jejunum.Differentiation-dependent regulation of the intestinal folate uptake process: studies with Caco-2 cells and native mouse intestine.Oligomeric structure of the human reduced folate carrier: identification of homo-oligomers and dominant-negative effects on carrier expression and function.Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size.Role of lysine 411 in substrate carboxyl group binding to the human reduced folate carrier, as determined by site-directed mutagenesis and affinity inhibition.The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.Uptake carriers and oncology drug safety.Genetic and epigenomic footprints of folate.Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function.Mutations in the reduced-folate carrier affect protein localization and stability.Confocal microscopy visualization of antifolate uptake by the reduced folate carrier in human leukaemic cells.Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family.Endocytosis of GPI-linked membrane folate receptor-alphaTranscript heterogeneity of the human reduced folate carrier results from the use of multiple promoters and variable splicing of alternative upstream exons.
P2860
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P2860
A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells
description
1994 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1994
@ast
im Januar 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/01/07)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/01/07)
@nl
наукова стаття, опублікована в січні 1994
@uk
name
A novel cDNA restores reduced ...... y to transport deficient cells
@ast
A novel cDNA restores reduced ...... y to transport deficient cells
@en
A novel cDNA restores reduced ...... y to transport deficient cells
@nl
type
label
A novel cDNA restores reduced ...... y to transport deficient cells
@ast
A novel cDNA restores reduced ...... y to transport deficient cells
@en
A novel cDNA restores reduced ...... y to transport deficient cells
@nl
prefLabel
A novel cDNA restores reduced ...... y to transport deficient cells
@ast
A novel cDNA restores reduced ...... y to transport deficient cells
@en
A novel cDNA restores reduced ...... y to transport deficient cells
@nl
P2093
P3181
P1476
A novel cDNA restores reduced ...... y to transport deficient cells
@en
P2093
P3181
P407
P577
1994-01-01T00:00:00Z