Role of rapsyn tetratricopeptide repeat and coiled-coil domains in self-association and nicotinic acetylcholine receptor clustering
about
Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner earRapsyn mutations in humans cause endplate acetylcholine-receptor deficiency and myasthenic syndromeA candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brainAlterations of cAMP-dependent signaling in dystrophic skeletal muscleStructure and superorganization of acetylcholine receptor-rapsyn complexesCrystal structure of c5321: a protective antigen present in uropathogenic Escherichia coli strains displaying an SLR foldCongenital myasthenic syndromes: pathogenesis, diagnosis, and treatmentInteractions of the rapsyn RING-H2 domain with dystroglycanA designed point mutant in Fis1 disrupts dimerization and mitochondrial fissionRapsyn carboxyl terminal domains mediate muscle specific kinase-induced phosphorylation of the muscle acetylcholine receptorOrigin of a folded repeat protein from an intrinsically disordered ancestorAChRs Are Essential for the Targeting of Rapsyn to the Postsynaptic Membrane of NMJs in Living MiceGα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signalingMechanism of acetylcholine receptor cluster formation induced by DC electric fieldGenes encoding Cher-TPR fusion proteins are predominantly found in gene clusters encoding chemosensory pathways with alternative cellular functions.Acetylcholine receptor organization in membrane domains in muscle cells: evidence for rapsyn-independent and rapsyn-dependent mechanisms.Myoblast fusion in Drosophila.Crosslinking-induced endocytosis of acetylcholine receptors by quantum dots.The actin binding domain of ACF7 binds directly to the tetratricopeptide repeat domains of rapsyn.Acetylcholine receptors enable the transport of rapsyn from the Golgi complex to the plasma membrane.Failure of lysosome clustering and positioning in the juxtanuclear region in cells deficient in rapsyn.alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering.Uncovering the lipidic basis for the preparation of functional nicotinic acetylcholine receptor detergent complexes for structural studiesMyasthenic syndrome due to defects in rapsyn: Clinical and molecular findings in 39 patientsRapsyn interacts with the muscle acetylcholine receptor via alpha-helical domains in the alpha, beta, and epsilon subunit intracellular loops.Structural mechanisms of the agrin-LRP4-MuSK signaling pathway in neuromuscular junction differentiation.The role of MuSK in synapse formation and neuromuscular disease.Moving forward with the neuromuscular junction.Exome sequencing positively identified relevant alterations in more than half of cases with an indication of prenatal ultrasound anomalies.Molecular determinants for PICK1 synaptic aggregation and mGluR7a receptor coclustering: role of the PDZ, coiled-coil, and acidic domains.Mechanosensitivity of nicotinic receptorsAgrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders.Removal of a consensus proline is not sufficient to allow tetratricopeptide repeat oligomerization.Spatial distribution and molecular dynamics of dystrophin glycoprotein components at the neuromuscular junction in vivo.Fundamental Molecules and Mechanisms for Forming and Maintaining Neuromuscular Synapses.Enzymatic Activity of the Scaffold Protein Rapsyn for Synapse Formation.Increased ratio of rapsyn to ACh receptor stabilizes postsynaptic receptors at the mouse neuromuscular synapse.Muscle-specific kinase (MuSK) autoantibodies suppress the MuSK pathway and ACh receptor retention at the mouse neuromuscular junction.
P2860
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P2860
Role of rapsyn tetratricopeptide repeat and coiled-coil domains in self-association and nicotinic acetylcholine receptor clustering
description
2001 nî lūn-bûn
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2001 թուականի Մարտին հրատարակուած գիտական յօդուած
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2001 թվականի մարտին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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name
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@ast
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@en
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@nl
type
label
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@ast
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@en
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@nl
prefLabel
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@ast
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@en
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@nl
P2093
P2860
P3181
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P1476
Role of rapsyn tetratricopepti ...... tylcholine receptor clustering
@en
P2093
M J Bianchetta
M K Ramarao
P2860
P304
P3181
P356
10.1074/JBC.M009888200
P407
P577
2001-03-09T00:00:00Z