Identification of Rho GTPase-dependent sites in the Dbl homology domain of oncogenic Dbl that are required for transformation
about
A molecular model for axon guidance based on cross talk between rho GTPases.Oligomerization of DH domain is essential for Dbl-induced transformationFGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane rufflesGene trapping identifies transiently induced survival genes during programmed cell deathTrp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factorsCharacterization of a brain-specific Rho GTPase-activating protein, p200RhoGAPOverexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liverDefective dendrite elongation but normal fertility in mice lacking the Rho-like GTPase activator Dbl.Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L.The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosisNovel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility.Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells.Autoinhibition mechanism of proto-Dbl.Involvement of SipA in modulating actin dynamics during Salmonella invasion into cultured epithelial cells.Amino acids of the bacterial toxin SopE involved in G nucleotide exchange on Cdc42.Signaling to the Rho GTPases: networking with the DH domain.Activation of Dbl restores migration in polyamine-depleted intestinal epithelial cells via Rho-GTPases.Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10).The guanine nucleotide exchange factor (GEF) Asef2 promotes dendritic spine formation via Rac activation and spinophilin-dependent targeting.A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death.Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency.Control of local Rho GTPase crosstalk by AbrMechanisms for concentrating Rho1 during cytokinesis.A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation.Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.Oligomerization regulates the localization of Cdc24, the Cdc42 activator in Saccharomyces cerevisiae.Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol.The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis
P2860
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P2860
Identification of Rho GTPase-dependent sites in the Dbl homology domain of oncogenic Dbl that are required for transformation
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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Identification of Rho GTPase-d ...... re required for transformation
@ast
Identification of Rho GTPase-d ...... re required for transformation
@en
Identification of Rho GTPase-d ...... re required for transformation
@nl
type
label
Identification of Rho GTPase-d ...... re required for transformation
@ast
Identification of Rho GTPase-d ...... re required for transformation
@en
Identification of Rho GTPase-d ...... re required for transformation
@nl
prefLabel
Identification of Rho GTPase-d ...... re required for transformation
@ast
Identification of Rho GTPase-d ...... re required for transformation
@en
Identification of Rho GTPase-d ...... re required for transformation
@nl
P2093
P356
P1476
Identification of Rho GTPase-d ...... re required for transformation
@en
P2093
P304
25993-6001
P356
10.1074/JBC.M003780200
P407
P577
2000-08-25T00:00:00Z