about
Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulationConstitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.Cross talk of tyrosine kinases with the DNA damage signaling pathwaysThe beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogeneRole of c-Abl in the DNA damage stress responseInactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-AblBiological Chemistry and Functionality of Protein Sulfenic Acids and Related Thiol ModificationsCellular processing of platinum anticancer drugsBinding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAblFunctional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response.TP53 NetworkATM Signaling PathwayThe NF-kappaB pathway blockade by the IKK inhibitor PS1145 can overcome imatinib resistance.c-Abl tyrosine kinase promotes adipocyte differentiation by targeting PPAR-gamma 2.Persistent inhibition of ABL tyrosine kinase causes enhanced apoptotic response to TRAIL and disrupts the pro-apoptotic effect of chloroquine.TP53 family members and human cancers.A positive role for c-Abl in Atm and Atr activation in DNA damage response.ATM: sounding the double-strand break alarm.ATM and ATR: sensing DNA damage.The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-β in mammary epithelial cellsThe c-Abl tyrosine kinase controls protein kinase Cδ-induced Fli-1 phosphorylation in human dermal fibroblasts.On the discovery, biological effects, and use of Cisplatin and metallocenes in anticancer chemotherapyc-abl is required for the development of hyperoxia-induced retinopathyThe p53 family in nervous system development and disease.Genetic studies of bone diseases: evidence for involvement of DNA damage response proteins in bone remodelingA role for c-Abl in cell senescence and spontaneous immortalization.The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains.c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expressionDNA damage stress response in germ cells: role of c-Abl and clinical implications.The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells.Saitohin, which is nested within the tau gene, interacts with tau and Abl and its human-specific allele influences Abl phosphorylation.Cleavage and phosphorylation: important post-translational modifications of galectin-3.c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitinationGalectin-3: A novel substrate for c-Abl kinase.Enterovirus 71 triggering of neuronal apoptosis through activation of Abl-Cdk5 signalling.Identification of TopBP1 as a c-Abl-interacting protein and a repressor for c-Abl expression.Insights into selective activation of p53 DNA binding by c-Abl.Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases.Attenuation of fibrosis with selective inhibition of c-Abl by siRNA in systemic sclerosis dermal fibroblasts.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
c-Abl: activation and nuclear targets
@ast
c-Abl: activation and nuclear targets
@en
c-Abl: activation and nuclear targets
@nl
type
label
c-Abl: activation and nuclear targets
@ast
c-Abl: activation and nuclear targets
@en
c-Abl: activation and nuclear targets
@nl
prefLabel
c-Abl: activation and nuclear targets
@ast
c-Abl: activation and nuclear targets
@en
c-Abl: activation and nuclear targets
@nl
P356
P1476
c-Abl: activation and nuclear targets
@en
P2093
P2888
P356
10.1038/SJ.CDD.4400626
P407
P577
2000-01-01T00:00:00Z