Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts
about
Distinctive activities of DNA polymerases during human DNA replicationThe cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replicationTreslin collaborates with TopBP1 in triggering the initiation of DNA replicationFunctional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiaeDistinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forksIsolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicaseA requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replicationStructure of the human GINS complex and its assembly and functional interface in replication initiationOrdered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins.Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeastDouble-stranded DNA binding properties of Saccharomyces cerevisiae DNA polymerase epsilon and of the Dpb3p-Dpb4p subassembly.Helicase loading at chromosomal origins of replicationRole of the p68 subunit of human DNA polymerase alpha-primase in simian virus 40 DNA replicationRPA is an initiation factor for human chromosomal DNA replication.Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication.Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.Protein phosphatase 2A regulates binding of Cdc45 to the prereplication complex.Assembly of the replication initiation complex on SV40 origin DNA.ATR and ATM regulate the timing of DNA replication origin firing.The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1.The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extractsXenopus Cdc6 performs separate functions in initiating DNA replicationContinued primer synthesis at stalled replication forks contributes to checkpoint activation.Control of chromosomal DNA replication in the early Xenopus embryo.Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response.Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extracts.DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeastThe ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.Control of DNA replication licensing in a cell cycle.Interactions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase.Human Cdc45 is a proliferation-associated antigen.Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication.The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast.Schizosacchromyces pombe Dpb2 binds to origin DNA early in S phase and is required for chromosomal DNA replicationEukaryotic MCM proteins: beyond replication initiation.DNA polymerase epsilon is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extractsRole for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extractsCdc45 is limiting for replication initiation in humansA novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication
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P2860
Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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Central role for cdc45 in esta ...... cation in Xenopus egg extracts
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10.1046/J.1365-2443.2000.00340.X
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P577
2000-06-01T00:00:00Z