Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor
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The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexiaDrosophila as a genetic and cellular model for studies on axonal growthMena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumorsIsolation and characterization of a novel class II histone deacetylase, HDAC10Dyslexia-associated kiaa0319-like protein interacts with axon guidance receptor nogo receptor 1ABL tyrosine kinases: evolution of function, regulation, and specificitySlit2-Robo4 signalling promotes vascular stability by blocking Arf6 activityCdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiationThe axonal repellent, Slit2, inhibits directional migration of circulating neutrophilsAbelson phosphorylation of CLASP2 modulates its association with microtubules and actinA WASp-VASP complex regulates actin polymerization at the plasma membrane.Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsionBinding site for Robo receptors revealed by dissection of the leucine-rich repeat region of SlitVilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axonsThe SLIT-ROBO pathway: a regulator of cell function with implications for the reproductive systemSlit-Robo interactions during cortical developmentInhibition of medulloblastoma cell invasion by SlitThe emerging role of Slit-Robo pathway in gastric and other gastro intestinal cancersTIPsy tour guides: how microtubule plus-end tracking proteins (+TIPs) facilitate axon guidanceThe Drosophila actin regulator ENABLED regulates cell shape and orientation during gonad morphogenesisMIG-10 functions with ABI-1 to mediate the UNC-6 and SLT-1 axon guidance signaling pathwaysThe Caenorhabditis elegans Eph receptor activates NCK and N-WASP, and inhibits Ena/VASP to regulate growth cone dynamics during axon guidanceTumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancersIncreased filamin binding to beta-integrin cytoplasmic domains inhibits cell migrationTyrosine phosphorylation of netrin receptors in netrin-1 signalingModulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extensionAbelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans.Structural basis of Robo proline-rich motif recognition by the srGAP1 Src homology 3 domain in the Slit-Robo signaling pathway.Critical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration.Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approachThe Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectinUnidirectional startle responses and disrupted left-right co-ordination of motor behaviors in robo3 mutant zebrafish.Ena drives invasive macrophage migration in Drosophila embryos.Ena/VASP function in retinal axons is required for terminal arborization but not pathway navigation.Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with FascinThe Abl/enabled signaling pathway regulates Golgi architecture in Drosophila photoreceptor neuronsSlit/Robo signaling modulates the proliferation of central nervous system progenitorsAbelson kinase regulates epithelial morphogenesis in Drosophila.A requirement for filopodia extension toward Slit during Robo-mediated axon repulsionThe VASP-Spred-Sprouty domain puzzle.
P2860
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P2860
Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@ast
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@en
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@nl
type
label
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@ast
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@en
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@nl
altLabel
Repulsive Axon Guidance
@ast
Repulsive Axon Guidance
@en
prefLabel
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@ast
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@en
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@nl
P2093
P50
P3181
P1433
P1476
Repulsive Axon Guidance
@en
Repulsive axon guidance: Abels ...... eam of the roundabout receptor
@en
P2093
C S Goodman
Corey S Goodman
Dave Murray
G J Bashaw
Greg J Bashaw
Thomas Kidd
P3181
P356
10.1016/S0092-8674(00)80883-1
P407
P577
2000-06-01T00:00:00Z
2000-06-23T00:00:00Z