Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
about
Kappa opioid antagonists: past successes and future prospectsFlavonoids as opioid receptor ligands: identification and preliminary structure-activity relationshipsKappa-opioid ligands in the study and treatment of mood disordersAntagonists of the kappa-opioid receptor enhance allodynia in rats and mice after sciatic nerve ligationMolecular switches of the κ opioid receptor triggered by 6'-GNTI and 5'-GNTI.Salvinorin A analogs as probes in opioid pharmacology.Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin AAnalogues of (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and in vitro and in vivo opioid receptor antagonist activityThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsPresynaptic inhibition of diverse afferents to the locus ceruleus by kappa-opiate receptors: a novel mechanism for regulating the central norepinephrine systemConformation-opioid activity relationships of bicyclic guanidines from 3D similarity analysis.A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase.Synthesis and pharmacological evaluation of 6-naltrexamine analogs for alcohol cessation.Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicityN-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonistsActivation of the opioid μ1, but not δ or κ, receptors is required for nicotine reinforcement in a rat model of drug self-administration.In vivo and in vitro characterization of naltrindole-derived ligands at the κ-opioid receptorDeletion of Ac-NMePhe(1) from [NMePhe(1) ]arodyn under acidic conditions, part 2: effects of substitutions on pharmacological activity.Development of κ opioid receptor antagonists.Natural products as tools for neuroscience: discovery and development of novel agents to treat drug abuseInvestigation of gastrin-releasing peptide as a mediator for 5'-guanidinonaltrindole-induced compulsive scratching in mice.Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials.Modification of the furan ring of salvinorin A: identification of a selective partial agonist at the kappa opioid receptor.Structure-activity relationships of arodyn, a novel acetylated kappa opioid receptor antagonist.Design, synthesis, and opioid activity of arodyn analogs cyclized by ring-closing metathesis involving Tyr(allyl).Cardiorenal Effects of Kappa Opioid Peptides During Ontogeny.Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists
P2860
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P2860
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@ast
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@en
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@nl
type
label
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@ast
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@en
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@nl
prefLabel
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@ast
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@en
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@nl
P2093
P356
P1476
Potent and selective indolomorphinan antagonists of the kappa-opioid receptor
@en
P2093
D M Ferguson
P S Portoghese
T G Metzger
W C Stevens
P304
P356
10.1021/JM0000665
P407
P577
2000-07-01T00:00:00Z