Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
about
Human BCAS3 expression in embryonic stem cells and vascular precursors suggests a role in human embryogenesis and tumor angiogenesisTex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpointComprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancerComplex formation by the human RAD51C and XRCC3 recombination repair proteinsChromosomal rearrangements and microRNAs: a new cancer link with clinical implicationsProgress in the application of DNA microarraysTreating breast cancer through novel inhibitors of the phosphatidylinositol 3'-kinase pathway.mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsDifferentially regulated genes as putative targets of amplifications at 20q in ovarian cancersRAD51C germline mutations in breast and ovarian cancer cases from high-risk familiesRelationships between signaling pathway usage and sensitivity to a pathway inhibitor: examination of trametinib responses in cultured breast cancer linesPotentiation of Growth Inhibitory Responses of the mTOR Inhibitor Everolimus by Dual mTORC1/2 Inhibitors in Cultured Breast Cancer Cell LinesThe p70S6K Specific Inhibitor PF-4708671 Impedes Non-Small Cell Lung Cancer GrowthThe level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cupDeciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancerPIK3CA and PIK3CB inhibition produce synthetic lethality when combined with estrogen deprivation in estrogen receptor-positive breast cancer.Detecting cancer gene networks characterized by recurrent genomic alterations in a population.Expressive genomic hybridisation: gene expression profiling at the cytogenetic levelAn inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice.MicroRNA expression and regulation in human ovarian carcinoma cells by luteinizing hormone.Overexpressed genes/ESTs and characterization of distinct amplicons on 17q23 in breast cancer cells.The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinasesMicroarray analysis: a novel research tool for cardiovascular scientists and physicians.High-throughput copy number analysis of 17q23 in 3520 tissue specimens by fluorescence in situ hybridization to tissue microarrays.Limited tissue fixation times and whole genomic amplification do not impact array CGH profilesFrozen tumor tissue microarray technology for analysis of tumor RNA, DNA, and proteins.T-box 2 expression predicts poor prognosis in gastric cancer.Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signalingThe T box transcription factor TBX2 promotes epithelial-mesenchymal transition and invasion of normal and malignant breast epithelial cells.Genomic evolution in Barrett's adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome.Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancerHigh-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer.Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients.M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier.Inherited and acquired alterations in development of breast cancer.The T-box transcription factors TBX2 and TBX3 in mammary gland development and breast cancerDysfunctional homologous recombination mediates genomic instability and progression in myeloma.Loss of Tbx2 delays optic vesicle invagination leading to small optic cups.Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival.Automated acquisition of stained tissue microarrays for high-throughput evaluation of molecular targets
P2860
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P2860
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
description
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Oktober 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: October 2000)
@en
vedecký článok (publikovaný 2000/10/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/10/01)
@nl
наукова стаття, опублікована в жовтні 2000
@uk
مقالة علمية (نشرت في أكتوبر 2000)
@ar
name
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@ast
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@en
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@nl
type
label
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@ast
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@en
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@nl
prefLabel
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@ast
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@en
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@nl
P2093
P1433
P1476
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer
@en
P2093
A Kallioniemi
J Torhorst
Kallioniemi OLLI-P
R Cornelison
P304
P407
P577
2000-10-01T00:00:00Z