The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding, and actin bundle formation
about
Drosophila as a genetic and cellular model for studies on axonal growthFyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeletonRegulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase IThe orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domainStructural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis proteinCDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASPMotility determinants in WASP family proteins.Actin-based motility of intracellular microbial pathogensThe VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeatActin dynamics in plateletsVASP protects actin filaments from gelsolin: an in vitro study with implications for platelet actin reorganizationsDual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinityEna/VASP: towards resolving a pointed controversy at the barbed endClustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation.Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteinsPivotal role of VASP in Arp2/3 complex-mediated actin nucleation, actin branch-formation, and Listeria monocytogenes motilityCell type-dependent mechanisms for formin-mediated assembly of filopodia.Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cellsHuman Mena associates with Rac1 small GTPase in glioblastoma cell linesThe solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domainsPhosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actinCharacterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteinsThere is more than one way to model an elephant. Experiment-driven modeling of the actin cytoskeletonMechanism of filopodia initiation by reorganization of a dendritic network.Vasodilator-Stimulated Phosphoprotein (VASP)-dependent and -independent pathways regulate thrombin-induced activation of Rap1b in plateletsVasodilator-stimulated phosphoprotein (VASP) induces actin assembly in dendritic spines to promote their development and potentiate synaptic strength.Ena/VASP proteins capture actin filament barbed ends.Ena/VASP proteins have an anti-capping independent function in filopodia formation.Critical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration.The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation.Exploring the roles of diaphanous and enabled activity in shaping the balance between filopodia and lamellipodia.Modeling capping protein FRAP and CALI experiments reveals in vivo regulation of actin dynamics.Molecular mechanism of Ena/VASP-mediated actin-filament elongation.Processive acceleration of actin barbed-end assembly by N-WASP.Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with FascinThe actin regulators Enabled and Diaphanous direct distinct protrusive behaviors in different tissues during Drosophila development.Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells.Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1.The VASP-Spred-Sprouty domain puzzle.
P2860
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P2860
The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding, and actin bundle formation
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@ast
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@en
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@nl
type
label
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@ast
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@en
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@nl
prefLabel
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@ast
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@en
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@nl
P2093
P3181
P356
P1476
The EVH2 domain of the vasodil ...... ng, and actin bundle formation
@en
P2093
P304
P3181
P356
10.1074/JBC.274.33.23549
P407
P577
1999-08-13T00:00:00Z