KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells
about
Insulin induces the release of vasodilator compounds from platelets by a nitric oxide-G kinase-VAMP-3-dependent pathwayRab13 regulates PKA signaling during tight junction assemblyImpairment of LTD and cerebellar learning by Purkinje cell-specific ablation of cGMP-dependent protein kinase IThe specificities of protein kinase inhibitors: an updateIn vivo regulation of renal expression of (pro)renin receptor by a low-sodium diet.Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha)cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells.KT5823 differentially modulates sodium iodide symporter expression, activity, and glycosylation between thyroid and breast cancer cells.p-Synephrine suppresses glucose production but not lipid accumulation in H4IIE liver cells.Dual wavelength photoactivation of cAMP- and cGMP-dependent protein kinase signaling pathways.Mechanism of glucose-6-phosphate dehydrogenase-mediated regulation of coronary artery contractility.Heterogeneous nuclear ribonucleoprotein A1 is a novel cellular target of atrial natriuretic peptide signaling in renal epithelial cells.Function of cGMP-dependent protein kinases in the nervous system.Glc-6-PD and PKG contribute to hypoxia-induced decrease in smooth muscle cell contractile phenotype proteins in pulmonary artery.Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytesRegulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G.The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells.β-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKGA proatherogenic role for cGMP-dependent protein kinase in vascular smooth muscle cells.Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide.Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome.cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment.cGMP-Dependent Protein Kinase Inhibitors in Health and Disease.cGMP signaling inhibits platelet shape change through regulation of the RhoA-Rho Kinase-MLC phosphatase signaling pathway.Involvement of the cGMP signalling pathway in the regulation of viability in insulin-secreting BRIN-BD11 cells.Autoinhibition and isoform-specific dominant negative inhibition of the type II cGMP-dependent protein kinase.Development of platelet inhibition by cAMP during megakaryocytopoiesis.Vasodilator-stimulated phosphoprotein (VASP) is phosphorylated on Ser157 by protein kinase C-dependent and -independent mechanisms in thrombin-stimulated human platelets.[EXPRESS] Cyclic GMP-dependent protein kinase-I localized in nociceptors modulates nociceptive cortical neuronal activity and pain hypersensitivity.YC-1 stimulates the expression of gaseous monoxide-generating enzymes in vascular smooth muscle cells.The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapsecGMP-mediated signaling via cGKIalpha is required for the guidance and connectivity of sensory axons.cGMP-dependent protein kinase type II regulates basal level of aldosterone production by zona glomerulosa cells without increasing expression of the steroidogenic acute regulatory protein gene.Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.Characterization of the L-arginine-NO-cGMP pathway in spontaneously hypertensive rat platelets: the effects of pregnancy.Sphingosylphosphorylcholine, a naturally occurring lipid mediator, inhibits human platelet function.A cGMP-dependent protein kinase assay for high throughput screening based on time-resolved fluorescence resonance energy transfer.Nitric oxide inhibits neuroendocrine Ca(V)1 L-channel gating via cGMP-dependent protein kinase in cell-attached patches of bovine chromaffin cells.Ca(2+)/calmodulin-dependent and cAMP-dependent kinases in induction of c-fos in human mesangial cells.
P2860
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P2860
KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@ast
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@en
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@nl
type
label
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@ast
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@en
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@nl
prefLabel
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@ast
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@en
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@nl
P2093
P50
P356
P1476
KT5823 inhibits cGMP-dependent ...... telets and rat mesangial cells
@en
P2093
A Palmetshofer
K Heermeier
M Burkhardt
T M Lincoln
T Vollkommer
P304
33536-33541
P356
10.1074/JBC.M005670200
P407
P577
2000-10-01T00:00:00Z