about
Evidence for concurrent effects of exposure to environmental cadmium and lead on hepatic CYP2A6 phenotype and renal function biomarkers in nonsmokers.Variable expression of CYP and Pgp genes in the human small intestinePolymorphisms of CYP2A6 and its practical consequencesSpecies differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactionsSummary of information on human CYP enzymes: human P450 metabolism data.Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.High CYP2A6 enzyme activity as measured by a caffeine test and unique distribution of CYP2A6 variant alleles in Ethiopian population.Efavirenz primary and secondary metabolism in vitro and in vivo: identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylationA novel CYP2A6 allele, CYP2A6*23, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descentAn experimental verification of the predicted effects of promoter TATA-box polymorphisms associated with human diseases on interactions between the TATA boxes and TATA-binding proteinHuman CYPs: in vivo and clinical aspects.Interindividual differences in nicotine metabolism and genetic polymorphisms of human CYP2A6.Interactions of herbs with cytochrome P450.Phenotypic CYP2A6 variation and the risk of pancreatic cancer.The emerging role of microRNAs in drug responsesDifferences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.Pharmacokinetic interactions between artesunate-mefloquine and ritonavir-boosted lopinavir in healthy Thai adultsHigh-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions.Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors.Past and future applications of CYP450-genetic polymorphisms for biomonitoring of environmental toxicants.The Relation between Hepatotoxicity and the Total Coumarin Intake from Traditional Japanese Medicines Containing Cinnamon Bark.Inter-individual Variability of Coumarin 7-hydroxylation (CYP2A6 activity) in an Iranian PopulationA comparison of substrate dynamics in human CYP2E1 and CYP2A6An overview of interactions between micronutrients and of micronutrients with drugs, genes and immune mechanisms.The role of human cytochrome P450 enzymes in the formation of 2-hydroxymetronidazole: CYP2A6 is the high affinity (low Km) catalystChemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity.Psychophysiological stress: a significant parameter in drug pharmacokinetics.Hormonal regulation of hepatic drug biotransformation and transport systems.A nicotine C-oxidase gene (CYP2A6) polymorphism important for promoter activity.Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity.Inhibitory potency of 8-methoxypsoralen on cytochrome P450 2A6 (CYP2A6) allelic variants CYP2A6 15, CYP2A6 16, CYP2A6 21 and CYP2A6 22: differential susceptibility due to different sequence locations of the mutations.Convergence of Free Energy Profile of Coumarin in Lipid Bilayer.A novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin.In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity.Hepatic CYP2B6 is altered by genetic, physiologic, and environmental factors but plays little role in nicotine metabolism.More potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde.Coumarins permeability in Caco-2 cell model.Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents.CYP2A6 activity in a healthy Spanish population: effect of age, sex, smoking, and oral contraceptives.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
CYP2A6: a human coumarin 7-hydroxylase
@ast
CYP2A6: a human coumarin 7-hydroxylase
@en
CYP2A6: a human coumarin 7-hydroxylase
@nl
type
label
CYP2A6: a human coumarin 7-hydroxylase
@ast
CYP2A6: a human coumarin 7-hydroxylase
@en
CYP2A6: a human coumarin 7-hydroxylase
@nl
prefLabel
CYP2A6: a human coumarin 7-hydroxylase
@ast
CYP2A6: a human coumarin 7-hydroxylase
@en
CYP2A6: a human coumarin 7-hydroxylase
@nl
P2093
P3181
P1433
P1476
CYP2A6: a human coumarin 7-hydroxylase
@en
P2093
P304
P3181
P356
10.1016/S0300-483X(99)00200-0
P407
P577
2000-04-03T00:00:00Z