TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG
about
Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEFEphexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanismA Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.Kinectin is a key effector of RhoG microtubule-dependent cellular activitySmall GTPase RhoG is a key regulator for neurite outgrowth in PC12 cellsSGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis.Immunological function in mice lacking the Rac-related GTPase RhoGEndogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration.The DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activationRho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular traffickingRho GAPs and GEFs: controling switches in endothelial cell adhesionFunction and regulation of the Rho guanine nucleotide exchange factor TrioThe N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.Apoptotic cell recognition receptors and scavenger receptors.Coordinate regulation of Salmonella enterica serovar Typhimurium invasion of epithelial cells by the Arp2/3 complex and Rho GTPases.The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation.RhoGDI3 and RhoG: Vesicular trafficking and interactions with the Sec3 Exocyst subunit.Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors.Integrin-linked kinase interactions with ELMO2 modulate cell polarityInteraction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells.Morphogenesis and regulation of Bergmann glial processes during Purkinje cell dendritic spine ensheathment and synaptogenesis.The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP.Myoblast fusion: when it takes more to make one.Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signalingIdentification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesisThe dual role of filamin A in cancer: can't live with (too much of) it, can't live without it.Identification of the GTPase-activating protein DEP domain containing 1B (DEPDC1B) as a transcriptional target of Pitx2Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos.The MET gene is a common integration target in avian leukosis virus subgroup J-induced chicken hemangiomas.M-cadherin activates Rac1 GTPase through the Rho-GEF trio during myoblast fusionHsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1.Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturationPolarized Rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis of C. elegans.High genomic instability predicts survival in metastatic high-risk neuroblastoma.Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function.Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowthKalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer.
P2860
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P2860
TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@ast
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@en
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@nl
type
label
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@ast
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@en
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@nl
prefLabel
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@ast
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@en
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@nl
P2093
P1476
TrioGEF1 controls Rac- and Cdc ...... the direct activation of rhoG
@en
P2093
P304
P407
P478
113 ( Pt 4)
P577
2000-02-01T00:00:00Z