MRE-Binding transcription factor-1: weak zinc-binding finger domains 5 and 6 modulate the structure, affinity, and specificity of the metal-response element complex
about
Zinc fingers can act as Zn2+ sensors to regulate transcriptional activation domain function.A novel cysteine cluster in human metal-responsive transcription factor 1 is required for heavy metal-induced transcriptional activation in vivoRegulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: identification of signal transduction cascades that control metal-inducible transcriptionAlternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activitiesZinc and cadmium can promote rapid nuclear translocation of metal response element-binding transcription factor-1Probing protein structure by amino acid-specific covalent labeling and mass spectrometry.The Drosophila homolog of mammalian zinc finger factor MTF-1 activates transcription in response to heavy metalsKnockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis.Putting its fingers on stressful situations: the heavy metal-regulatory transcription factor MTF-1.The transcription factors MTF-1 and USF1 cooperate to regulate mouse metallothionein-I expression in response to the essential metal zinc in visceral endoderm cells during early developmentEffect of His-Tag on Expression, Purification, and Structure of Zinc Finger Protein, ZNF191(243-368)Target gene search for the metal-responsive transcription factor MTF-1.Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells.Efficient metal-specific transcription activation by Drosophila MTF-1 requires conserved cysteine residues in the carboxy-terminal domain.Cellular sensing and transport of metal ions: implications in micronutrient homeostasis.A fluorescence resonance energy transfer-derived structure of a quantum dot-protein bioconjugate nanoassemblyCopper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster.Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein.Metal-responsive transcription factor 1 (MTF-1) activity is regulated by a nonconventional nuclear localization signal and a metal-responsive transactivation domain.The "magic numbers" of metallothionein.Zinc'ing sensibly: controlling zinc homeostasis at the transcriptional level.Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc.Nuclear factor-1 and metal transcription factor-1 synergistically activate the mouse metallothionein-1 gene in response to metal ions.The zinc-sensing mechanism of mouse MTF-1 involves linker peptides between the zinc fingers.Identification and functional characterization of MRE-binding transcription factor (MTF) in Crassostrea gigas and its conserved role in metal-induced response.Native and engineered sensors for Ca2+ and Zn2+: lessons from calmodulin and MTF1.Mammalian metal response element-binding transcription factor-1 functions as a zinc sensor in yeast, but not as a sensor of cadmium or oxidative stress.Dynamics of the metal-dependent transcription factor complex in vivo at the mouse metallothionein-I promoter.Gene- and cell-type-specific effects of signal transduction cascades on metal-regulated gene transcription appear to be independent of changes in the phosphorylation of metal-response-element-binding transcription factor-1.The six zinc fingers of metal-responsive element binding transcription factor-1 form stable and quasi-ordered structures with relatively small differences in zinc affinities.Functional heterogeneity in the zinc fingers of metalloregulatory protein metal response element-binding transcription factor-1.Metal binding properties of zinc fingers with a naturally altered metal binding site.TvZNF1 is a C2H2 zinc finger protein of Trichomonas vaginalis.Putative zinc-sensing zinc fingers of metal-response element-binding transcription factor-1 stabilize a metal-dependent chromatin complex on the endogenous metallothionein-I promoter.Cadmium‐induced gene expression is regulated by MTF‐1, a key metal‐responsive transcription factor
P2860
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P2860
MRE-Binding transcription factor-1: weak zinc-binding finger domains 5 and 6 modulate the structure, affinity, and specificity of the metal-response element complex
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
MRE-Binding transcription fact ...... metal-response element complex
@ast
MRE-Binding transcription fact ...... metal-response element complex
@en
MRE-Binding transcription fact ...... metal-response element complex
@nl
type
label
MRE-Binding transcription fact ...... metal-response element complex
@ast
MRE-Binding transcription fact ...... metal-response element complex
@en
MRE-Binding transcription fact ...... metal-response element complex
@nl
prefLabel
MRE-Binding transcription fact ...... metal-response element complex
@ast
MRE-Binding transcription fact ...... metal-response element complex
@en
MRE-Binding transcription fact ...... metal-response element complex
@nl
P3181
P356
P1433
P1476
MRE-Binding transcription fact ...... metal-response element complex
@en
P304
12915-12925
P3181
P356
10.1021/BI9913000
P407
P577
1999-09-01T00:00:00Z