AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
about
Wnt signaling pathways in urological cancers: past decades and still growingMutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signallingIdentification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidneyEpigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instabilitySoluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicinActivation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signalingSubcellular distribution of Wnt pathway proteins in normal and neoplastic colonIdentification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cellsEpidermal growth factor receptor regulates beta-catenin location, stability, and transcriptional activity in oral cancerI-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferationOncogenic function of DACT1 in colon cancer through the regulation of β-cateninMicrosomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axisThe Axin1 scaffold protein promotes formation of a degradation complex for c-MycHDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencingFunctional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cellsPrognostic significance of BMP and activin membrane-bound inhibitor in colorectal cancerThe beta-catenin binding protein ICAT modulates androgen receptor activityWNT10B functional dualism: beta-catenin/Tcf-dependent growth promotion or independent suppression with deregulated expression in cancerNegative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells.HMG box transcriptional repressor HBP1 maintains a proliferation barrier in differentiated liver tissueAxin facilitates Smad3 activation in the transforming growth factor beta signaling pathwayIsolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesisInsight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liverStructural basis of the Axin-adenomatous polyposis coli interactionWnt/beta-catenin signaling and small molecule inhibitorsARID2: a new tumor suppressor gene in hepatocellular carcinomaWnt/beta-catenin signaling: components, mechanisms, and diseasesCrystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complexAstrocyte elevated gene-1 regulates hepatocellular carcinoma development and progressionThe Wnt-dependent signaling pathways as target in oncology drug discoveryR-Etodolac decreases beta-catenin levels along with survival and proliferation of hepatoma cellsThe links between axin and carcinogenesisA functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the beta-catenin signaling pathwayNr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesisEpidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liverAxin and GSK3- control Smad3 protein stability and modulate TGF- signalingWnt signaling in breast cancer: have we come full circle?The Wnts
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P2860
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@ast
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@en
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@nl
type
label
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@ast
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@en
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@nl
prefLabel
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@ast
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@en
AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@nl
P2093
P2860
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AXIN1 mutations in hepatocellu ...... rus-mediated transfer of AXIN1
@en
P2093
H Ishiguro
T Nishiwaki
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P304
P3181
P356
10.1038/73448
P407
P577
2000-03-01T00:00:00Z