Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling - Wikidata - wikimedia - TriplyDB

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

http://www.wikidata.org/entity/Q28146183

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Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription The Ski protein family is required for MeCP2-mediated transcriptional repression DACH1 inhibits transforming growth factor-beta signaling through binding Smad4 The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasm Sumoylated SnoN represses transcription in a promoter-specific manner The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3 Local network topology in human protein interaction data predicts functional association Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1 The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF.Ski interacts with the evolutionarily conserved SNW domain of Skip Regulation of myostatin activity and muscle growth Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway Transforming growth factor-beta and breast cancer: Transforming growth factor-beta/SMAD signaling defects and cancer.The Tgif2 gene contains a retained intron within the coding sequence.HER-2 overexpression differentially alters transforming growth factor-beta responses in luminal versus mesenchymal human breast cancer cells TGF-β signaling in C. elegans Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis Interplay of retinal determination gene network with TGF-β signaling pathway in epithelial-mesenchymal transition Activation-induced nuclear translocation of RING3 Repression of TGF-beta signaling by the oncogenic protein SKI in human melanomas: consequences for proliferation, survival, and metastasis Direct interaction of Ski with either Smad3 or Smad4 is necessary and sufficient for Ski-mediated repression of transforming growth factor-beta signaling TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation c-Jun associates with the oncoprotein Ski and suppresses Smad2 transcriptional activity TGIF2 interacts with histone deacetylase 1 and represses transcription Crossing Smads Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1 Competition between Ski and CREB-binding protein for binding to Smad proteins in transforming growth factor-beta signaling A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene Corl1, a novel neuronal lineage-specific transcriptional corepressor for the homeodomain transcription factor Lbx1 The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice

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P2860

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

http://www.wikidata.org/entity/Q28146183

description

1999 nî lūn-bûn

@nan

1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

@ast

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

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Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

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type

label

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

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Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

@en

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

@nl

prefLabel

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

@ast

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

@en

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

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Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

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E N Eaton

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W S Lane

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X Liu

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Y Sun

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scholarly article

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10.1016/S1097-2765(00)80201-4

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4

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Robert Weinberg

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1999-10-01T00:00:00Z

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10549282

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