Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
about
Second nature: biological functions of the Raf-1 "kinase"The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell deathAberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanismsCoordinating ERK/MAPK signalling through scaffolds and inhibitorsThe RAF proteins take centre stageSrc42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism.Ras-association domain family 1 protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation.Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.How Genetics Has Helped Piece Together the MAPK Signaling Pathway.The CNK2 scaffold interacts with vilse and modulates Rac cycling during spine morphogenesis in hippocampal neurons.Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signalingThe CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation.A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.Loss-of-Function CNKSR2 Mutation Is a Likely Cause of Non-Syndromic X-Linked Intellectual Disability.Mechanistic principles of RAF kinase signaling.CNK1 is a novel Akt interaction partner that promotes cell proliferation through the Akt-FoxO signalling axis.Absent CNKSR2 causes seizures and intellectual, attention, and language deficits.
P2860
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P2860
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@ast
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@en
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@nl
type
label
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@ast
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@en
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@nl
prefLabel
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@ast
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@en
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@nl
P2093
P921
P356
P1433
P1476
Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf
@en
P2093
Albert Liu
Ben Margolis
Kun-Liang Guan
Thomas M Lanigan
Yang Z Huang
P304
P356
10.1096/FJ.02-1096COM
P407
P577
2003-11-01T00:00:00Z