Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf - Wikidata - wikimedia - TriplyDB

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

http://www.wikidata.org/entity/Q28181747

about

Second nature: biological functions of the Raf-1 "kinase"The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms Coordinating ERK/MAPK signalling through scaffolds and inhibitors The RAF proteins take centre stage Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism.Ras-association domain family 1 protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation.Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.How Genetics Has Helped Piece Together the MAPK Signaling Pathway.The CNK2 scaffold interacts with vilse and modulates Rac cycling during spine morphogenesis in hippocampal neurons.Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1 CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation.A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.Loss-of-Function CNKSR2 Mutation Is a Likely Cause of Non-Syndromic X-Linked Intellectual Disability.Mechanistic principles of RAF kinase signaling.CNK1 is a novel Akt interaction partner that promotes cell proliferation through the Akt-FoxO signalling axis.Absent CNKSR2 causes seizures and intellectual, attention, and language deficits.

P2860

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P2860

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

http://www.wikidata.org/entity/Q28181747

description

2003 nî lūn-bûn

@nan

2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@ast

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@en

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@nl

type

label

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@ast

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@en

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@nl

prefLabel

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@ast

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@en

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@nl

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P1476

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

@en

P2093

Albert Liu

http://www.w3.org/2001/XMLSchema#string

Ben Margolis

http://www.w3.org/2001/XMLSchema#string

Kun-Liang Guan

http://www.w3.org/2001/XMLSchema#string

Lin Mei

http://www.w3.org/2001/XMLSchema#string

Thomas M Lanigan

http://www.w3.org/2001/XMLSchema#string

Yang Z Huang

http://www.w3.org/2001/XMLSchema#string

P304

2048-60

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1096/FJ.02-1096COM

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P433

14

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17

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P577

2003-11-01T00:00:00Z

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P5875

5368000

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14597674

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P921

intracellular signal transduction

Connector enhancer of kinase suppressor of Ras 2