Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance
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SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradationSuppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signalingThe E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteinsInflammation, stress, and diabetesDeletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardationTwo Drosophila suppressors of cytokine signaling (SOCS) differentially regulate JAK and EGFR pathway activitiesThe role of suppressors of cytokine signalling in human neoplasmsSOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune FunctionSuppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signalingAging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophyHIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitusSuppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanismsInsulin and GH signaling in human skeletal muscle in vivo following exogenous GH exposure: impact of an oral glucose loadPim3 negatively regulates glucose-stimulated insulin secretionActivation of SOCS-3 by resistinExperimental endotoxemia induces adipose inflammation and insulin resistance in humans.Increases in insulin sensitivity among obese youth are associated with gene expression changes in whole blood.Knock your SOCS off!Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial.The role of adipose tissue and adipokines in obesity-related inflammatory diseasesSuppressor of cytokine signalling-6 promotes neurite outgrowth via JAK2/STAT5-mediated signalling pathway, involving negative feedback inhibition.Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistanceSatellite cells derived from obese humans with type 2 diabetes and differentiated into myocytes in vitro exhibit abnormal response to IL-6.Mathematical modeling of corticosteroid pharmacogenomics in rat muscle following acute and chronic methylprednisolone dosingInhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice.FOXO1 content is reduced in cystic fibrosis and increases with IGF-I treatment.Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention.Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis.Growth hormone signal transduction.Activation of peroxisome proliferator-activated receptor-β/-δ (PPAR-β/-δ) ameliorates insulin signaling and reduces SOCS3 levels by inhibiting STAT3 in interleukin-6-stimulated adipocytes.A new role for SOCS in insulin action. Suppressor of cytokine signaling.SOCS-1 deficiency does not prevent diet-induced insulin resistance.Are SOCS suppressors, regulators, and degraders?MiR-19a regulates PTEN expression to mediate glycogen synthesis in hepatocytes.Expression and suppressive effects of interleukin-19 on vascular smooth muscle cell pathophysiology and development of intimal hyperplasia.Temporal profiling of the transcriptional basis for the development of corticosteroid-induced insulin resistance in rat muscle.SOCS regulation of the JAK/STAT signalling pathway.Molecular signatures of obstructive sleep apnea in adults: a review and perspective.
P2860
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P2860
Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@ast
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@en
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@nl
type
label
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@ast
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@en
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@nl
prefLabel
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@ast
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@en
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@nl
P2093
P2860
P356
P1476
Suppressors of cytokine signal ...... ne-mediated insulin resistance
@en
P2093
L M Boivin
R A Mooney
R W Furlanetto
P2860
P304
P356
10.1074/JBC.M010579200
P407
P577
2001-07-13T00:00:00Z