Interaction of human pancreatic ribonuclease with human ribonuclease inhibitor. Generation of inhibitor-resistant cytotoxic variants
about
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor proteinStructural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variantFunctional role of glutamine 28 and arginine 39 in double stranded RNA cleavage by human pancreatic ribonuclease.Antitumor activity of ribonuclease multimers created by site-specific covalent tethering.The expression and localization of RNase and RNase inhibitor in blood cells and vascular endothelial cells in homeostasis of the vascular system.Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicityEvaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform.Covalent cross-linking of proteins without chemical reagents.Insertional-fusion of basic fibroblast growth factor endowed ribonuclease 1 with enhanced cytotoxicity by steric blockade of inhibitor interaction.An insertion in loop L7 of human eosinophil-derived neurotoxin is crucial for its antiviral activity.New anti-CD30 human pancreatic ribonuclease-based immunotoxin reveals strong and specific cytotoxicity in vivo.Endowing human pancreatic ribonuclease with toxicity for cancer cells.RNase1 as a potential mediator of remote ischaemic preconditioning for cardioprotection†.Targeted therapeutic RNases (ImmunoRNases)
P2860
Q24299746-09A95A82-63AB-44B5-9594-C8A5917EE929Q27653585-3414DC89-DC66-43EE-A80C-CCC279D7C0B7Q33847531-29084FED-5905-402D-A84B-ACDB470A9381Q34130092-80B08D41-52B6-44EE-A683-92AA261C0F9DQ36318506-B9CA8E33-6676-4773-AD28-D33F711BE471Q37233080-0B3B58F4-ADEB-4EC8-B2DA-AE3E19212DD0Q37698918-FDDFAC40-5FEE-425B-96C0-708F9058A082Q38269957-BBB1364F-949A-4260-9767-F1211F4893A8Q38340108-82A1C5B6-139C-4429-A625-9C710A6937A4Q39348912-B002C6C9-7217-4F6F-A81E-776293D3597FQ40118023-A8FDF0BD-8D87-46F7-BF48-B63023CFBCE0Q43736485-B584FD97-3C93-45DC-ABE1-9B86715A4722Q47766407-D40CB2CB-4C94-4AFC-8F11-9DDA79A0026FQ58008126-3F53C480-C5E1-46AA-9621-B28E488CFED6
P2860
Interaction of human pancreatic ribonuclease with human ribonuclease inhibitor. Generation of inhibitor-resistant cytotoxic variants
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Interaction of human pancreati ...... r-resistant cytotoxic variants
@ast
Interaction of human pancreati ...... r-resistant cytotoxic variants
@en
Interaction of human pancreati ...... r-resistant cytotoxic variants
@nl
type
label
Interaction of human pancreati ...... r-resistant cytotoxic variants
@ast
Interaction of human pancreati ...... r-resistant cytotoxic variants
@en
Interaction of human pancreati ...... r-resistant cytotoxic variants
@nl
prefLabel
Interaction of human pancreati ...... r-resistant cytotoxic variants
@ast
Interaction of human pancreati ...... r-resistant cytotoxic variants
@en
Interaction of human pancreati ...... r-resistant cytotoxic variants
@nl
P2093
P2860
P356
P1476
Interaction of human pancreati ...... r-resistant cytotoxic variants
@en
P2093
P2860
P304
P356
10.1074/JBC.M102440200
P407
P577
2001-07-06T00:00:00Z