A tumour-derived mutant allele of XRCC2 preferentially suppresses homologous recombination at DNA replication forks
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Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stabilitySignificant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival.Homologous recombination is necessary for normal lymphocyte development.MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair.Transcription-associated recombination is independent of XRCC2 and mechanistically separate from homology-directed DNA double-strand break repair.Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells.
P2860
A tumour-derived mutant allele of XRCC2 preferentially suppresses homologous recombination at DNA replication forks
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2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A tumour-derived mutant allele ...... ation at DNA replication forks
@ast
A tumour-derived mutant allele ...... ation at DNA replication forks
@en
A tumour-derived mutant allele ...... ation at DNA replication forks
@nl
type
label
A tumour-derived mutant allele ...... ation at DNA replication forks
@ast
A tumour-derived mutant allele ...... ation at DNA replication forks
@en
A tumour-derived mutant allele ...... ation at DNA replication forks
@nl
prefLabel
A tumour-derived mutant allele ...... ation at DNA replication forks
@ast
A tumour-derived mutant allele ...... ation at DNA replication forks
@en
A tumour-derived mutant allele ...... ation at DNA replication forks
@nl
P2093
P356
P1476
A tumour-derived mutant allele ...... ation at DNA replication forks
@en
P2093
Atul Mohindra
Emma Bolderson
Jason Stone
Mark Meuth
Michael Wells
P304
P356
10.1093/HMG/DDH022
P407
P577
2004-01-15T00:00:00Z