OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
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A critical role for OX40 in T cell-mediated immunopathology during lung viral infectionThe intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the gamesCD134 as target for specific drug delivery to auto-aggressive CD4+ T cells in adjuvant arthritisThe role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosisRoles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degenerationImproving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer VaccinationRegulators of Tfh Cell Differentiation4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicityThe costimulation-regulated duration of PKB activation controls T cell longevityComparison of OX40 ligand and CD70 in the promotion of CD4+ T cell responsesBim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasisDual anti-OX40/IL-2 therapy augments tumor immunotherapy via IL-2R-mediated regulation of OX40 expressionLymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.Stimulation of naive CD8+ T cells by a variant viral epitope induces activation and enhanced apoptosisDeciphering c-MYC-regulated genes in two distinct tissues.Effect of natalizumab on circulating CD4+ T-cells in multiple sclerosis.Detailed analysis of gene expression during development of T cell lineages in the thymus.Tentative T cells: memory cells are quick to respond, but slow to divideMemory T-cell-specific therapeutics in organ transplantation.Control of immunity by the TNFR-related molecule OX40 (CD134)CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse.Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension.Costimulatory pathways in transplantation.Activation of OX40 augments Th17 cytokine expression and antigen-specific uveitis.Interactions between the intestinal microbiota and innate lymphoid cells.OX40 facilitates control of a persistent virus infection.Targeting CD8+ T-cell tolerance for cancer immunotherapy.OX40 costimulation can abrogate Foxp3+ regulatory T cell-mediated suppression of antitumor immunity.Soluble OX40L is associated with presence of autoantibodies in early rheumatoid arthritisSignals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment.Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cellsOX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.Regulation of A1 by OX40 contributes to CD8(+) T cell survival and anti-tumor activity.The significance of OX40 and OX40L to T-cell biology and immune disease.CD127+CCR5+CD38+++ CD4+ Th1 effector cells are an early component of the primary immune response to vaccinia virus and precede development of interleukin-2+ memory CD4+ T cells.PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer.OX40 ligand expressed in glioblastoma modulates adaptive immunity depending on the microenvironment: a clue for successful immunotherapy.Apoptosis and transplantation tolerance.STAT3 protein promotes T-cell survival and inhibits interleukin-2 production through up-regulation of Class O Forkhead transcription factors.Targeting OX40 promotes lung-resident memory CD8 T cell populations that protect against respiratory poxvirus infection
P2860
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P2860
OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
description
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im September 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: September 2001)
@en
vedecký článok (publikovaný 2001-09)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd in 2001-09)
@nl
наукова стаття, опублікована у вересні 2001
@uk
مقالة علمية (نشرت في سبتمبر 2001)
@ar
name
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@ast
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@en
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@nl
type
label
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@ast
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@en
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@nl
prefLabel
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@ast
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@en
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@nl
P2093
P3181
P1433
P1476
OX40 promotes Bcl-xL and Bcl-2 ...... g-term survival of CD4 T cells
@en
P2093
P304
P3181
P356
10.1016/S1074-7613(01)00191-1
P407
P577
2001-09-01T00:00:00Z