The role of Six1 in mammalian auditory system development
about
A symphony of inner ear developmental control genes.SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexesThe Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1Molecular mechanisms of inner ear developmentSegregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Where hearing starts: the development of the mammalian cochleaTranscriptional regulation of cranial sensory placode developmentThe DACH/EYA/SIX gene network and its role in tumor initiation and progressionEya 1 acts as a critical regulator for specifying the metanephric mesenchymeEYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner earSIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome.Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodesJxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of cortiSix1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesisEya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner earEya4-deficient mice are a model for heritable otitis media.Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1Six proteins regulate the activation of Myf5 expression in embryonic mouse limbsWnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh.Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients.Using Xenopus to discover new genes involved in branchiootorenal spectrum disordersShaping sound in space: the regulation of inner ear patterningThe sine oculis homeobox (SIX) family of transcription factors as regulators of development and diseaseKeeping sensory cells and evolving neurons to connect them to the brain: molecular conservation and novelties in vertebrate ear developmentGenetic Correction of Induced Pluripotent Stem Cells From a Deaf Patient With MYO7A Mutation Results in Morphologic and Functional Recovery of the Derived Hair Cell-Like Cells.Signaling and Transcription Factors during Inner Ear Development: The Generation of Hair Cells and Otic Neurons.Connecting the ear to the brain: Molecular mechanisms of auditory circuit assembly.The role of foxi family transcription factors in the development of the ear and jaw.Histone deacetylase inhibitor induces the expression of select epithelial genes in mouse utricle sensory epithelia-derived progenitor cells.Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.Redundant functions of Rac GTPases in inner ear morphogenesisBalancing cell numbers during organogenesis: Six1a differentially affects neurons and sensory hair cells in the inner ear.Expression of the Pax2 transcription factor is associated with vestibular phenotype in the avian inner earHeadbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness.Regeneration of Hair Cells: Making Sense of All the Noise.RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.Reconstruction of the mouse otocyst and early neuroblast lineage at single-cell resolution.The mouse Foxi3 transcription factor is necessary for the development of posterior placodes.Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis.
P2860
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P2860
The role of Six1 in mammalian auditory system development
description
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im September 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: September 2003)
@en
vedecký článok (publikovaný 2003-09)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd in 2003-09)
@nl
наукова стаття, опублікована у вересні 2003
@uk
مقالة علمية (نشرت في سبتمبر 2003)
@ar
name
The role of Six1 in mammalian auditory system development
@ast
The role of Six1 in mammalian auditory system development
@en
The role of Six1 in mammalian auditory system development
@nl
type
label
The role of Six1 in mammalian auditory system development
@ast
The role of Six1 in mammalian auditory system development
@en
The role of Six1 in mammalian auditory system development
@nl
prefLabel
The role of Six1 in mammalian auditory system development
@ast
The role of Six1 in mammalian auditory system development
@en
The role of Six1 in mammalian auditory system development
@nl
P2093
P2860
P3181
P356
P1433
P1476
The role of Six1 in mammalian auditory system development
@en
P2093
Bihui Tang
Derek Silvius
Pin-Xian Xu
Weiming Zheng
Zhu-Bo Wei
P2860
P304
P3181
P356
10.1242/DEV.00628
P407
P577
2003-09-01T00:00:00Z