Investigation of conserved acidic residues in 3-hydroxy-3-methylglutaryl-CoA lyase: implications for human disease and for functional roles in a family of related proteins
about
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosolCrystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduriaFunctional Insights into Human HMG-CoA Lyase from Structures of Acyl-CoA-containing Ternary ComplexesInfluence of multiple cysteines on human 3-hydroxy-3-methylglutaryl-CoA lyase activity and formation of inter-subunit adductsThe 3-hydroxy-methylglutaryl coenzyme A lyase HCL1 is required for macrophage colonization by human fungal pathogen Histoplasma capsulatum.Mechanistic and bioinformatic investigation of a conserved active site helix in α-isopropylmalate synthase from Mycobacterium tuberculosis, a member of the DRE-TIM metallolyase superfamily.Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds.Utility of acetyldithio-CoA in detecting the influence of active site residues on substrate enolization by 3-hydroxyl-3-methylglutaryl-CoA synthase.
P2860
Q24294455-861F232C-7D1A-41B5-ADCA-B579709F2E44Q24298101-7C8646F8-EDFA-4416-8FCF-CE2135684C31Q27662433-6247A14C-E264-4E7E-A635-2DE1191711D4Q35089041-C1AB906E-AC64-40C7-AEDB-21296A192F52Q36558767-0E67FE0E-3C8E-4484-94C7-B1126507DF1DQ39728797-6FE5F808-20C2-4A72-B0CF-45F17208E080Q42674861-E170D023-B55B-43C4-A16D-221267C2BAE7Q44973212-C7964218-1E37-49B9-A3D1-7966B9CD7FBD
P2860
Investigation of conserved acidic residues in 3-hydroxy-3-methylglutaryl-CoA lyase: implications for human disease and for functional roles in a family of related proteins
description
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im September 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 26 September 2003)
@en
vedecký článok (publikovaný 2003/09/26)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/09/26)
@nl
наукова стаття, опублікована у вересні 2003
@uk
name
Investigation of conserved aci ...... n a family of related proteins
@ast
Investigation of conserved aci ...... n a family of related proteins
@en
Investigation of conserved aci ...... n a family of related proteins
@nl
type
label
Investigation of conserved aci ...... n a family of related proteins
@ast
Investigation of conserved aci ...... n a family of related proteins
@en
Investigation of conserved aci ...... n a family of related proteins
@nl
prefLabel
Investigation of conserved aci ...... n a family of related proteins
@ast
Investigation of conserved aci ...... n a family of related proteins
@en
Investigation of conserved aci ...... n a family of related proteins
@nl
P2860
P356
P1476
Investigation of conserved aci ...... n a family of related proteins
@en
P2093
Henry M Miziorko
Robbyn L Tuinstra
P2860
P304
P356
10.1074/JBC.M304472200
P407
P577
2003-09-26T00:00:00Z