Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells

Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells

Item
http://www.wikidata.org/entity/Q28190037
Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factorsPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersIncreased expression of the hPim-2 gene in human chronic lymphocytic leukemia and non-Hodgkin lymphomaThe oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpointThe serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitorPim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.Genomic microarrays: arraying order in biological chaos?EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferationPIM1 gene cooperates with human BCL6 gene to promote the development of lymphomasInhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammationDifferential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases.PIM-1-specific mAb suppresses human and mouse tumor growth by decreasing PIM-1 levels, reducing Akt phosphorylation, and activating apoptosis.Nuclear and mitochondrial signalling Akts in cardiomyocytesRole of protein-tyrosine phosphatases in regulation of osteoclastic activity.Insights from Pim1 structure for anti-cancer drug design.Loss of PIM1 correlates with progression and prognosis of salivary adenoid cystic carcinoma (SACC).Pim1 permits generation and survival of CD4+ T cells in the absence of γc cytokine receptor signaling.
P2860

Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells

Item
http://www.wikidata.org/entity/Q28190037
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@ast
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@en
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@nl
type
label
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@ast
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@en
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@nl
prefLabel
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@ast
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@en
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921