Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells
about
Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factorsPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersIncreased expression of the hPim-2 gene in human chronic lymphocytic leukemia and non-Hodgkin lymphomaThe oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpointThe serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitorPim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.Genomic microarrays: arraying order in biological chaos?EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferationPIM1 gene cooperates with human BCL6 gene to promote the development of lymphomasInhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammationDifferential regulation of androgen receptor by PIM-1 kinases via phosphorylation-dependent recruitment of distinct ubiquitin E3 ligases.PIM-1-specific mAb suppresses human and mouse tumor growth by decreasing PIM-1 levels, reducing Akt phosphorylation, and activating apoptosis.Nuclear and mitochondrial signalling Akts in cardiomyocytesRole of protein-tyrosine phosphatases in regulation of osteoclastic activity.Insights from Pim1 structure for anti-cancer drug design.Loss of PIM1 correlates with progression and prognosis of salivary adenoid cystic carcinoma (SACC).Pim1 permits generation and survival of CD4+ T cells in the absence of γc cytokine receptor signaling.
P2860
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P2860
Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
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Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@en
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
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Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@ast
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@en
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@nl
prefLabel
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@ast
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@en
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
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P2093
P356
P1476
Pim-1 negatively regulates the ...... of monoblastoid leukemia cells
@en
P2093
P356
10.1006/ABBI.2001.2370
P407
P577
2001-06-01T00:00:00Z