The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function
about
PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phaseTxk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cellsThe HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammationA macrodomain-containing histone rearranges chromatin upon sensing PARP1 activationHyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processingChemokine-cytokine cross-talk. The ELR+ CXC chemokine LIX (CXCL5) amplifies a proinflammatory cytokine response via a phosphatidylinositol 3-kinase-NF-kappa B pathwayNF-κB potentiates caspase independent hydrogen peroxide induced cell deathArginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expressionEssential role of poly(ADP-ribosyl)ation in cocaine actionIdentification of poly(ADP-ribose)polymerase-1 and Ku70/Ku80 as transcriptional regulators of S100A9 gene expressionRegulation of poly(ADP-ribose) polymerase-1 (PARP-1) gene expression through the post-translational modification of Sp1: a nuclear target protein of PARP-1The nucleosome-remodeling ATPase ISWI is regulated by poly-ADP-ribosylation.Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cellsPoly(ADP-ribose) polymerase-1 and its cleavage products differentially modulate cellular protection through NF-kappaB-dependent signalingFunctional Aspects of PARP1 in DNA Repair and Transcription.Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes.Interaction of Sindbis virus non-structural protein 3 with poly(ADP-ribose) polymerase 1 in neuronal cells.Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia.Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation.PARP-1 enhances the mismatch-dependence of 5'-directed excision in human mismatch repair in vitroNew facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.Absence of poly(ADP-ribose) polymerase 1 delays the onset of Salmonella enterica serovar Typhimurium-induced gut inflammationActivation of poly(ADP-ribose) polymerase-1 delays wound healing by regulating keratinocyte migration and production of inflammatory mediators.Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly(ADP-ribose) polymerase-1 activation and neuronal death.Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation.PARP-1 inhibitors DPQ and PJ-34 negatively modulate proinflammatory commitment of human glioblastoma cells.PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B.Absence of poly(ADP-ribose)polymerase-1 alters nuclear factor-kappa B activation and gene expression of apoptosis regulators after reperfusion injury.ZIC2-dependent transcriptional regulation is mediated by DNA-dependent protein kinase, poly(ADP-ribose) polymerase, and RNA helicase A.Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line.PARP-1 modulates amyloid beta peptide-induced neuronal damage.Poly(ADP-ribose) polymerase 1-sirtuin 1 functional interplay regulates LPS-mediated high mobility group box 1 secretion.Fine tuning the transcriptional regulation of the CXCL1 chemokinePARP1 activation/expression modulates regional-specific neuronal and glial responses to seizure in a hemodynamic-independent manner.17β estradiol regulates adhesion molecule expression in mesangial cells during glomerulonephritis.Poly(ADP-ribosyl)ation inhibitors: promising drug candidates for a wide variety of pathophysiologic conditions.Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase.ARTD1 Suppresses Interleukin 6 Expression by Repressing MLL1-Dependent Histone H3 Trimethylation.
P2860
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P2860
The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The enzymatic and DNA binding ...... F-kappa B coactivator function
@ast
The enzymatic and DNA binding ...... F-kappa B coactivator function
@en
The enzymatic and DNA binding ...... F-kappa B coactivator function
@nl
type
label
The enzymatic and DNA binding ...... F-kappa B coactivator function
@ast
The enzymatic and DNA binding ...... F-kappa B coactivator function
@en
The enzymatic and DNA binding ...... F-kappa B coactivator function
@nl
prefLabel
The enzymatic and DNA binding ...... F-kappa B coactivator function
@ast
The enzymatic and DNA binding ...... F-kappa B coactivator function
@en
The enzymatic and DNA binding ...... F-kappa B coactivator function
@nl
P2093
P2860
P356
P1476
The enzymatic and DNA binding ...... F-kappa B coactivator function
@en
P2093
P2860
P304
P356
10.1074/JBC.M106528200
P407
P577
2001-12-07T00:00:00Z