Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2

Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2

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http://www.wikidata.org/entity/Q28193566
Q28168244
sameAs
Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimerIdentification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivitySynthesis of 7-thiaarachidonic acid as a mechanistic probe of prostaglandin H synthase-2.Crystal Structure of Aspirin-Acetylated Human Cyclooxygenase-2: Insight into the Formation of Products with Reversed Stereochemistry.Control of oxygenation in lipoxygenase and cyclooxygenase catalysisProstaglandin H synthase: resolved and unresolved mechanistic issues.Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2.Cyclooxygenase reaction mechanism of PGHS--evidence for a reversible transition between a pentadienyl radical and a new tyrosyl radical by nitric oxide trapping.Histidine 386 and its role in cyclooxygenase and peroxidase catalysis by prostaglandin-endoperoxide H synthases.Identification of two cyclooxygenase active site residues, Leucine 384 and Glycine 526, that control carbon ring cyclization in prostaglandin biosynthesis.Role of Asn-382 and Thr-383 in activation and inactivation of human prostaglandin H synthase cyclooxygenase catalysis.
P2860

Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2

Item
http://www.wikidata.org/entity/Q28193566
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structural characterization of ...... ted prostaglandin H synthase-2
@ast
Structural characterization of ...... ted prostaglandin H synthase-2
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Structural characterization of ...... ted prostaglandin H synthase-2
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type
label
Structural characterization of ...... ted prostaglandin H synthase-2
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Structural characterization of ...... ted prostaglandin H synthase-2
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Structural characterization of ...... ted prostaglandin H synthase-2
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prefLabel
Structural characterization of ...... ted prostaglandin H synthase-2
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Structural characterization of ...... ted prostaglandin H synthase-2
@en
Structural characterization of ...... ted prostaglandin H synthase-2
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P1476
P2093
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Structural characterization of ...... ted prostaglandin H synthase-2
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P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921