Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: implications for the development and treatment of atherosclerosis
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The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinctSterol metabolism controls T(H)17 differentiation by generating endogenous RORγ agonistsIdentification of novel regulatory cholesterol metabolite, 5-cholesten, 3β,25-diol, disulfate7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fract7-Ketocholesterol is present in lipid deposits in the primate retina: potential implication in the induction of VEGF and CNV formationIdentification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands.Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degenerationExtract of Kuding tea prevents high-fat diet-induced metabolic disorders in C57BL/6 mice via liver X receptor (LXR) β antagonism.Adipocyte enhancer-binding protein 1 (AEBP1) (a novel macrophage proinflammatory mediator) overexpression promotes and ablation attenuates atherosclerosis in ApoE (-/-) and LDLR (-/-) miceDifferential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells.The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors--relevance to Parkinson's disease.Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophilesLiver X receptors and fat cell metabolism.Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties.Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver x receptor activationSulfation of 25-hydroxycholesterol regulates lipid metabolism, inflammatory responses, and cell proliferation.Liver X Receptor: Crosstalk Node for the Signaling of Lipid Metabolism, Carbohydrate Metabolism, and Innate Immunity.Revisiting cobalt chloride preconditioning to prevent hypobaric hypoxia-induced damage: identification of global proteomic alteration and key networks.MicroRNAs in dysfunctional adipose tissue: cardiovascular implications.Okra polysaccharide improves metabolic disorders in high-fat diet-induced obese C57BL/6 mice.Emerging Roles for MicroRNAs in Diabetic Microvascular Disease: Novel Targets for Therapy.Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux.Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARgamma ligands.Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer.Orphan nuclear receptors, PXR and LXR: new ligands and therapeutic potential.Liver X receptor activation attenuates plaque formation and improves vasomotor function of the aortic artery in atherosclerotic ApoE(-/-) mice.27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons.Transgenic Overexpression of Steroid Sulfatase Alleviates Cholestasis
P2860
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P2860
Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: implications for the development and treatment of atherosclerosis
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@ast
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@en
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@nl
type
label
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@ast
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@en
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@nl
prefLabel
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@ast
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@en
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@nl
P2093
P1433
P1476
Auto-oxidized cholesterol sulf ...... d treatment of atherosclerosis
@en
P2093
P356
10.1016/S0039-128X(00)00239-7
P407
P577
2001-06-01T00:00:00Z