Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome
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Human INT6/eIF3e is required for nonsense-mediated mRNA decayPhosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosisPCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexesThe Arabidopsis COP9 Signalosome Subunit 7 Is a Model PCI Domain Protein with Subdomains Involved in COP9 Signalosome AssemblyThe crystal structure of the MPN domain from the COP9 signalosome subunit CSN6COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae.Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination.Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregationTranslation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit.The proto-oncogene Int6 is essential for neddylation of Cul1 and Cul3 in Drosophila.Cell cycle-related variation in subcellular localization of eIF3e/INT6 in human fibroblasts.Expression of truncated eukaryotic initiation factor 3e (eIF3e) resulting from integration of mouse mammary tumor virus (MMTV) causes a shift from cap-dependent to cap-independent translation.INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cellsINT6 interacts with MIF4GD/SLIP1 and is necessary for efficient histone mRNA translation.INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells.The Drosophila orthologue of the INT6 onco-protein regulates mitotic microtubule growth and kinetochore structure.RETRACTED: The COP9 signalosome interacts with and regulates interferon regulatory factor 5 protein stability.HAF : the new player in oxygen-independent HIF-1alpha degradation.The eIF3 interactome reveals the translasome, a supercomplex linking protein synthesis and degradation machineries.Activation of AP-1-dependent transcription by a truncated translation initiation factor.Roles of Multifunctional COP9 Signalosome Complex in Cell Fate and Implications for Drug Discovery.Int6 regulates both proteasomal degradation and translation initiation and is critical for proper formation of acini by human mammary epithelium.A forward genetic screen identifies eukaryotic translation initiation factor 3, subunit H (eIF3h), as an enhancer of variegation in the mouse.Translational regulation via 5' mRNA leader sequences revealed by mutational analysis of the Arabidopsis translation initiation factor subunit eIF3h.Arabidopsis eIF3e interacts with subunits of the ribosome, Cop9 signalosome and proteasome.Corrected and Republished from: The COP9 Signalosome Interacts with and Regulates Interferon Regulatory Factor 5 Protein Stability.The COP9 signalosome: its regulation of cullin-based E3 ubiquitin ligases and role in photomorphogenesis.
P2860
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P2860
Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome
description
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im September 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 11 September 2002)
@en
vedecký článok (publikovaný 2002/09/11)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/09/11)
@nl
наукова стаття, опублікована у вересні 2002
@uk
مقالة علمية (نشرت في 11-9-2002)
@ar
name
Association of the mammalian p ...... signalosome and 26S proteasome
@ast
Association of the mammalian p ...... signalosome and 26S proteasome
@en
Association of the mammalian p ...... signalosome and 26S proteasome
@nl
type
label
Association of the mammalian p ...... signalosome and 26S proteasome
@ast
Association of the mammalian p ...... signalosome and 26S proteasome
@en
Association of the mammalian p ...... signalosome and 26S proteasome
@nl
prefLabel
Association of the mammalian p ...... signalosome and 26S proteasome
@ast
Association of the mammalian p ...... signalosome and 26S proteasome
@en
Association of the mammalian p ...... signalosome and 26S proteasome
@nl
P2093
P2860
P1433
P1476
Association of the mammalian p ...... signalosome and 26S proteasome
@en
P2093
Karine Hoareau Alves
Pierre Jalinot
Valérie Bochard
P2860
P356
10.1016/S0014-5793(02)03147-2
P407
P577
2002-09-01T00:00:00Z