Death by deamination: a novel host restriction system for HIV-1
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Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodiesTranscription-coupled mutagenesis by the DNA deaminase AIDThe human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activitiesHuman APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replicationA second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteinsHuman APOBEC3G can restrict retroviral infection in avian cells and acts independently of both UNG and SMUG1Role of Zn2+ ions in host-virus interactionsDual inhibitory effects of APOBEC family proteins on retrotransposition of mammalian endogenous retrovirusesCurrent perspectives on HIV-1 antiretroviral drug resistanceCyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCFcyclin F E3 Ligase MachineryG-->A hypermutation in protease and reverse transcriptase regions of human immunodeficiency virus type 1 residing in resting CD4+ T cells in vivoThe cellular protein daxx interacts with avian sarcoma virus integrase and viral DNA to repress viral transcription.Human cytomegalovirus UL130 protein promotes endothelial cell infection through a producer cell modification of the virion.Replication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNAProfile of Stephen P. Goff. Interview by Greg WilliamsThe Vif and Vpr accessory proteins independently cause HIV-1-induced T cell cytopathicity and cell cycle arrestBiochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect.Drug resistance mutations in drug-naive HIV type 1 subtype C-infected individuals from rural MalawiIntrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons.Catalytic analysis of APOBEC3G involving real-time NMR spectroscopy reveals nucleic acid determinants for deamination.APOBEC3G targets specific virus species.Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family.Genetic variants in the host restriction factor APOBEC3G are associated with HIV-1-related disease progression and central nervous system impairment in children.Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection.Mechanisms of DNA damage, repair, and mutagenesis.Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence.APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase.Role of APOBEC3G/F-mediated hypermutation in the control of human immunodeficiency virus type 1 in elite suppressors.
P2860
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P2860
Death by deamination: a novel host restriction system for HIV-1
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2003 nî lūn-bûn
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2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2003 թվականի օգոստոսին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年论文
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Death by deamination: a novel host restriction system for HIV-1
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Death by deamination: a novel host restriction system for HIV-1
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Death by deamination: a novel host restriction system for HIV-1
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Death by deamination: a novel host restriction system for HIV-1
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Death by deamination: a novel host restriction system for HIV-1
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Death by deamination: a novel host restriction system for HIV-1
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Death by deamination: a novel host restriction system for HIV-1
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Death by deamination: a novel host restriction system for HIV-1
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Death by deamination: a novel host restriction system for HIV-1
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P1433
P1476
Death by deamination: a novel host restriction system for HIV-1
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P2093
Stephen P Goff
P407
P577
2003-08-08T00:00:00Z